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IDS 抗体 (C-Term)

IDS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042998
发货至: 中国
  • 抗原 See all IDS 抗体
    IDS (Iduronate 2-Sulfatase (IDS))
    抗原表位
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 430-448, C-Term
    适用
    • 38
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    宿主
    • 28
    • 9
    • 3
    克隆类型
    • 34
    • 6
    多克隆
    标记
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDS antibody is un-conjugated
    应用范围
    • 39
    • 14
    • 13
    • 13
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Iduronate 2-sulfatase(IDS) detection. Tested with WB, IHC-P in Human.
    序列
    ELCREGKNLL KHFRFRDLE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Iduronate 2-sulfatase(IDS) detection. Tested with WB, IHC-P in Human.
    Gene Name: iduronate 2-sulfatase
    Protein Name: Iduronate 2-sulfatase
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase(430-448aa ELCREGKNLLKHFRFRDLE).
    亚型
    IgG
    Top Product
    Discover our top product IDS Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    IDS (Iduronate 2-Sulfatase (IDS))
    别名
    IDS (IDS 产品)
    别名
    mps2 antibody, sids antibody, zgc:158245 antibody, MPS2 antibody, SIDS antibody, AW214631 antibody, iduronate 2-sulfatase antibody, IDS antibody, CpipJ_CPIJ004938 antibody, ids antibody, Ids antibody
    背景
    IDS(Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al.(1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al.(1992) and Daniele et al.(1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.

    Synonyms: Alpha L iduronate sulfate sulfatase antibody|Alpha-L-iduronate sulfate sulfatase antibody|AW214631 antibody|Ids antibody|IDS_HUMAN antibody|Iduronate 2 sulfatase 14 kDa chain antibody|Iduronate 2 sulfatase 42 kDa chain antibody|Iduronate 2 sulfatase antibody|Iduronate 2-sulfatase 14 kDa chain antibody|Iduronate sulfatase antibody|Idursulfase antibody|MPS2 antibody|RP23-29M4.1 antibody|SIDS antibody
    UniProt
    P22304
    途径
    Glycosaminoglycan Metabolic Process
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