-
- 抗原 See all IDS 抗体
- IDS (Iduronate 2-Sulfatase (IDS))
-
抗原表位
- AA 430-448, C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IDS antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-Iduronate 2 sulfatase/IDS Antibody Picoband®
- 序列
- ELCREGKNLL KHFRFRDLE
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-Iduronate 2 sulfatase/IDS Antibody (ABIN3042998). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase.
- 亚型
- IgG
- Top Product
- Discover our top product IDS Primary Antibody
-
anti-Iduronate 2-Sulfatase (IDS) (AA 95-289) antibody
IDS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) antibodyIDS 适用: 人, 小鼠 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Iduronate 2-Sulfatase (IDS) antibodyIDS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 4G2 unconjugated
anti-Iduronate 2-Sulfatase (IDS) (AA 1-550) antibodyIDS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) (Internal Region) antibodyVerified IDS 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) antibodyIDS 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) (AA 38-137) antibodyIDS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) antibodyIDS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Iduronate 2-Sulfatase (IDS) (AA 1-312) antibodyIDS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Iduronate 2-Sulfatase (IDS) (AA 1-550) antibodyIDS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Daniele, A., Faust, C. J., Herman, G. E., Di Natale, P., Ballabio, A. Cloning and characterization of the cDNA for the murine iduronate sulfatase gene. Genomics 16: 755-757, 1993. 2. Faust, C. J., Verkerk, A. J. M. H., Wilson, P. J., Morris, C. P., Hopwood, J. J., Oostra, B. A., Herman, G. E. Genetic mapping on the mouse X chromosome of human cDNA clones for the fragile X and Hunter syndromes. Genomics 12: 814-817, 1992. 3. Wilson, P. J., Suthers, G. K., Callen, D. F., Baker, E., Nelson, P. V., Cooper, A., Wraith, J. E., Sutherland, G. R., Morris, C. P., Hopwood, J. J. Frequent deletions at Xq28 indicate genetic heterogeneity in Hunter syndrome. Hum. Genet. 86: 505-508, 1991. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
-
- 抗原
- IDS (Iduronate 2-Sulfatase (IDS))
- 别名
- IDS (IDS 产品)
- 背景
-
Synonyms: Iduronate 2-sulfatase,3.1.6.13,Alpha-L-iduronate sulfate sulfatase,Idursulfase,Iduronate 2-sulfatase 42 kDa chain,Iduronate 2-sulfatase 14 kDa chain,IDS,SIDS,
Tissue Specificity: Liver, kidney, lung, and placenta.
Background: IDS (Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al. (1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al. (1992) and Daniele et al. (1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.
Sequence Similarities: Contains 2 follistatin-like domains.
- 分子量
- 22-24 kDa
- UniProt
- P22304
- 途径
- Glycosaminoglycan Metabolic Process
-
You are here:
