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HSC70 Interacting Protein HIP 抗体 (N-Term)

ST13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042991
发货至: 中国
  • 抗原 See all HSC70 Interacting Protein HIP (ST13) 抗体
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    抗原表位
    • 15
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    AA 1-19, N-Term
    适用
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    宿主
    • 36
    • 9
    克隆类型
    • 37
    • 8
    多克隆
    标记
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    This HSC70 Interacting Protein HIP antibody is un-conjugated
    应用范围
    • 44
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Hsc70-interacting protein(ST13) detection. Tested with WB in Human.
    序列
    MDPRKVNELR AFVKMCKQD
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Hsc70-interacting protein(ST13) detection. Tested with WB in Human.
    Gene Name: suppression of tumorigenicity 13(colon carcinoma)(Hsp70 interacting protein)
    Protein Name: Hsc70-interacting protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human ST13(1-19aa MDPRKVNELRAFVKMCKQD), different from the related rat and mouse sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ST13 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    别名
    ST13 (ST13 产品)
    别名
    CG32789 antibody, Dmel\\CG32789 antibody, anon-EST:fe1A9 antibody, 1110007I03Rik antibody, 3110002K08Rik antibody, AW555194 antibody, HIP antibody, HOP antibody, HSPABP antibody, HSPABP1 antibody, PRO0786 antibody, SNC6 antibody, p48 antibody, AAG2 antibody, FAM10A1 antibody, FAM10A4 antibody, P48 antibody, Hsc/Hsp70-interacting protein antibody, suppression of tumorigenicity 13 antibody, ST13, Hsp70 interacting protein antibody, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) antibody, HIP antibody, St13 antibody, ST13 antibody
    背景
    ST13(Suppression of Tumorigenicity 13), also known as P48 or HIP, is a protein that in humans is encoded by the ST13 gene. ST13 is an abundant, highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD(HSP70) and HSP90 during an intermediate stage of steroid receptor assembly, but is absent from the mature receptor complex. Zhang et al.(1998) mapped the ST13 gene to chromosome 22q13 by fluorescence in situ hybridization. They noted that colorectal, breast, and ovarian carcinomas frequently show loss of heterozygosity at this site. Using a yeast 2-hybrid assay, Hohfeld et al.(1995) showed that rat Hip bound Hsc70(HSPA8). One Hip oligomer bound the ATPase domains of at least 2 Hsc70 Molecules, and binding was dependent on activation of the Hsc70 ATPase by Hsp40(DNAJB1). Hip stabilized the ADP-bound form of Hsc70, which had a high affinity for a test protein substrate. Hohfeld et al.(1995) concluded that HIP contributes to interactions of HSC70 with target proteins through its own chaperone activity.

    Synonyms: AAG 2 antibody|AAG2 antibody|Aging associated protein 2 antibody|F10A1_HUMAN antibody|FAM10A1 antibody|FAM10A4 antibody|FLJ27260 antibody|Heat shock 70kD protein binding protein antibody|HIP antibody|HOP antibody|Hsc70 interacting protein antibody|Hsc70-interacting protein antibody|Hsp70 interacting protein antibody|HSPABP 1 antibody|HSPABP antibody|HSPABP1 antibody|MGC129952 antibody|OTTHUMP00000028873 antibody|P48 antibody|PRO0786 antibody|Progesterone receptor associated p48 protein antibody|Progesterone receptor-associated p48 protein antibody|Protein FAM10A1 antibody|Putative tumor suppressor ST13 antibody|Renal carcinoma antigen NY REN 33 antibody|Renal carcinoma antigen NY-REN-33 antibody|SNC 6 antibody|SNC6 antibody|ST 13 antibody|ST13 antibody|Suppression of tumorigenicity 13 antibody|Suppression of tumorigenicity 13(colon carcinoma) antibody|Suppression of tumorigenicity 13 protein antibody|Suppression of tumorigenicity protein 13 antibody
    UniProt
    P50502
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