电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CXCR5 抗体 (C-Term)

This anti-CXCR5 antibody is a 兔 多克隆 antibody detecting CXCR5 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3042947
发货至: 中国

Quick Overview for CXCR5 抗体 (C-Term) (ABIN3042947)

抗原

See all CXCR5 抗体
CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

适用

  • 100
  • 52
  • 46
  • 5
  • 5
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 12
  • 3
  • 2
  • 1

克隆类型

  • 61
  • 42
  • 1
多克隆

标记

  • 38
  • 8
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This CXCR5 antibody is un-conjugated

应用范围

  • 51
  • 33
  • 28
  • 13
  • 12
  • 8
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 12
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 358-372, C-Term

    原理

    Anti-CXCR5 Antibody Picoband®

    序列

    SSLSESENAT SLTTF

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-CXCR5 Antibody (ABIN3042947). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Allen, C. D. C., Ansel, K. M., Low, C., Lesley, R., Tamamura, H., Fujii, N., Cyster, J. G. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nature Immun. 5: 943-952, 2004. 2. Chan, C.-C., Shen, D., Hackett, J. J., Buggage, R. R., Tuaillon, N. Expression of chemokine receptors, CXCR4 and CXCR5, and chemokines, BLC and SDF-1, in the eyes of patients with primary intraocular lymphoma. Ophthalmology 110: 421-426, 2003. 3. Reif, K., Ekland, E. H., Ohl, L., Nakano, H., Lipp, M., Forster, R., Cyster, J. G. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature 416: 94-99, 2002.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

    别名

    CXCR5

    背景

    Synonyms: C-X-C chemokine receptor type 5,CXC-R5,CXCR-5,Burkitt lymphoma receptor 1,Monocyte-derived receptor 15,MDR-15,CD185,CXCR5,BLR1, MDR15,

    Tissue Specificity: Expression in mature B-cells and Burkitt lymphoma cells.

    Background: CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al. (2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al. (2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma (PIOL).

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    分子量

    22 kDa

    UniProt

    P32302
You are here:
Chat with us!