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ABI2 抗体 (N-Term)

This anti-ABI2 antibody is a 兔 多克隆 antibody detecting ABI2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3042919
发货至: 中国

Quick Overview for ABI2 抗体 (N-Term) (ABIN3042919)

抗原

See all ABI2 抗体
ABI2 (Abl-Interactor 2 (ABI2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ABI2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 158-173, N-Term

    原理

    Anti-Abl interactor 2 ABI2 Antibody Picoband®

    序列

    RFKVSTQNMK MGGLPR

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Abl interactor 2 ABI2 Antibody (ABIN3042919). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Dai, Z., Pendergast, A. M. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes Dev. 9: 2569-2582, 1995. 2. Machado, R. D., Pauciulo, M. W., Fretwell, N., Veal, C., Thomson, J. R., Guell, C. V., Aldred, M., Brannon, C. A., the International PPH Consortium, Trembath, R. C., Nichols, W. C. A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. Genomics 68: 220-228, 2000.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ABI2 (Abl-Interactor 2 (ABI2))

    别名

    ABI2

    背景

    Synonyms: Abl interactor 2,Abelson interactor 2,Abi-2,Abl-binding protein 3,AblBP3,Arg-binding protein 1,ArgBP1,ABI2,ARGBPIA,

    Tissue Specificity: Highly expressed in brain tissues with the exception of the spinal cord. .

    Background: ABI2 (ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al. (2000) mapped the ABI2 gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein, a central serine-rich region, 3 PEST sequences, which are implicated in susceptibility to protein degradation, several proline-rich stretches, and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast (1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

    Sequence Similarities: Belongs to the ABI family.

    分子量

    60 kDa
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