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CXCR1 抗体 (N-Term)

CXCR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042912
发货至: 中国
  • 抗原 See all CXCR1 抗体
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    抗原表位
    • 15
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-38, N-Term
    适用
    • 38
    • 17
    • 10
    • 1
    • 1
    宿主
    • 37
    • 5
    • 3
    克隆类型
    • 41
    • 3
    • 1
    多克隆
    标记
    • 25
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR1 antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 13
    • 13
    • 12
    • 11
    • 11
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1(CXCR1) detection. Tested with WB, IHC-P in Human.
    序列
    DEDYSPCMLE TETLN
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1(CXCR1) detection. Tested with WB, IHC-P in Human.
    Gene Name: chemokine(C-X-C motif) receptor 1
    Protein Name: C-X-C chemokine receptor type 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1(24-38aa DEDYSPCMLETETLN).
    亚型
    IgG
    Top Product
    Discover our top product CXCR1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
    别名
    CXCR1 (CXCR1 产品)
    别名
    C-C antibody, C-C-CKR-1 antibody, CD128 antibody, CD181 antibody, CDw128a antibody, CKR-1 antibody, CMKAR1 antibody, IL8R1 antibody, IL8RA antibody, IL8RBA antibody, Il8ra antibody, CXCR-1 antibody, IL-8RA antibody, CXCR2 antibody, IL8RB antibody, cxcr1 antibody, cxcr2 antibody, C-X-C motif chemokine receptor 1 antibody, chemokine (C-X-C motif) receptor 1 antibody, C-X-C chemokine receptor type 1 antibody, C-X-C motif chemokine receptor 1 S homeolog antibody, CXCR1 antibody, Cxcr1 antibody, LOC100461947 antibody, cxcr1.S antibody
    背景
    CXCR1(Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al.(1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.

    Synonyms: C C antibody|C C CKR 1 antibody|C-X-C chemokine receptor type 1 antibody|CCCKR1 antibody|CD 181 antibody|CD128 antibody|CD181 antibody|CD181 antigen antibody|CDw128a antibody|Chemokine(C X C motif) receptor 1 antibody|Chemokine(C X C) receptor 1 antibody|Chemokine receptor 1 antibody|CKR 1 antibody|CMKAR1 antibody|CXC-R1 antibody|CXCR 1 antibody|CXCR-1 antibody|CXCR1 antibody|CXCR1_HUMAN antibody|High affinity interleukin 8 receptor A antibody|High affinity interleukin-8 receptor A antibody|IL 8 receptor type 1 antibody|IL 8R A antibody|IL-8 receptor type 1 antibody|IL-8R A antibody|IL8 receptor antibody|IL8 receptor type 1 antibody|IL8R1 antibody|IL8RA antibody|IL8RBA antibody|Interleukin 8 receptor alpha antibody|Interleukin 8 receptor type 1 antibody|Interleukin 8 receptor type A antibody
    UniProt
    P25024
    途径
    cAMP Metabolic Process
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