Ataxin 2 抗体 (C-Term)
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Quick Overview for Ataxin 2 抗体 (C-Term) (ABIN3042901)
抗原
See all Ataxin 2 (ATXN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1293-1313, C-Term
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原理
- Anti-ATX2/ATXN2 Antibody
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序列
- TTAHFPYMTH PSVQAHHQQQ L
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ATX2/ATXN2 Antibody (ABIN3042901). Tested in Flow Cytometry , IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ATX2, identical to the related mouse sequence.
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亚型
- IgG
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anti-Ataxin 2 (ATXN2) (AA 775-856) antibody
ATXN2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyVerified ATXN2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 174-383) antibodyATXN2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyATXN2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 321-355) antibodyATXN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53600 unconjugated
anti-Ataxin 2 (ATXN2) (AA 725-757) antibodyATXN2 适用: 人 WB 宿主: 兔 Polyclonal RB53601 unconjugated
anti-Ataxin 2 (ATXN2) (AA 1214-1313) antibodyATXN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Middle Region) antibodyATXN2 适用: 人, 小鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Center) antibodyATXN2 适用: 人, 猴 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Middle Region) antibodyATXN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Ataxin 2 (ATXN2)
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别名
- ATXN2
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背景
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Synonyms: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2, SCA2, TNRC13,
Tissue Specificity: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .
Background: Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.
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分子量
- 140-150 kDa
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UniProt
- Q99700
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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