SDC3 抗体 (N-Term)
(2 references)Quick Overview for SDC3 抗体 (N-Term) (ABIN3042886)
抗原
See all SDC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-60, N-Term
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原理
- Anti-Syndecan 3/SDC3 Antibody Picoband®
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序列
- AQRWRNENFE RPVDLE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Syndecan 3/SDC3 Antibody (ABIN3042886). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse Syndecan 3/SDC3, identical to the related rat sequence, and different from the related human sequence by one amino acid.
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亚型
- IgG
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anti-Syndecan 3 (SDC3) (N-Term) antibody
SDC3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 3 (SDC3) (AA 27-76) antibodySDC3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 3 (SDC3) antibodySDC3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 3 (SDC3) antibodySDC3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Syndecan 3 (SDC3) (N-Term) antibodySDC3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Berndt, C., Casaroli-Marano, R. P., Vilaro, S., Reina, M. Cloning and characterization of human syndecan-3. J. Cell. Biol. 82: 246-259, 2001. 2. Bobardt, M. D., Saphire, A. C. S., Hung, H.-C., Yu, X., Van der Schueren, B., Zhang, Z., David, G., Gallay, P. A. Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity 18: 27-39, 2003. 3. de Witte, L., Bobardt, M., Chatterji, U., Degeest, G., David, G., Geijtenbeek, T. B. H., Gallay, P. Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1.Proc. Nat. Acad. Sci. 104: 19464-19469, 2007. 4. Ha, E., Kim, M.-J., Choi, B.-K., Rho, J.-J., Oh, D.-J., Rho, T.-H., Kim, K.-H., Lee, H. J., Shin, D.-H., Yim, S. V., Baik, H. H., Chung, J.-H., Kim, J. W. Positive association of obesity with single nucleotide polymorphisms of syndecan 3 in the Korean population. J. Clin. Endocr. Metab. 91: 5095-5099, 2006. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Pleiotrophin and N-syndecan promote perineural invasion and tumor progression in an orthotopic mouse model of pancreatic cancer." in: World journal of gastroenterology, Vol. 23, Issue 21, pp. 3907-3914, (2017) (PubMed).
: "Midkine promotes perineural invasion in human pancreatic cancer." in: World journal of gastroenterology, Vol. 20, Issue 11, pp. 3018-24, (2014) (PubMed).
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: "Pleiotrophin and N-syndecan promote perineural invasion and tumor progression in an orthotopic mouse model of pancreatic cancer." in: World journal of gastroenterology, Vol. 23, Issue 21, pp. 3907-3914, (2017) (PubMed).
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- SDC3 (Syndecan 3 (SDC3))
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别名
- SDC3
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背景
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Synonyms: Syndecan-3,SYND3,Sdc3,Kiaa0468,
Tissue Specificity: Expressed in most tissues. Most abundant in kidney, bone and liver.
Background: Syndecan-3, also called SYND3 is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
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分子量
- 60 kDa
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UniProt
- Q64519
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途径
- Glycosaminoglycan Metabolic Process
抗原
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