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HIF3A 抗体 (C-Term)

The 兔 多克隆 anti-HIF3A antibody is suitable to detect HIF3A in samples from 人 和 大鼠. It has been validated for WB.
产品编号 ABIN3042875
发货至: 中国
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Quick Overview for HIF3A 抗体 (C-Term) (ABIN3042875)

抗原

See all HIF3A 抗体
HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

适用

  • 47
  • 30
  • 23
  • 1
人, 大鼠

宿主

  • 44
  • 4
  • 1

克隆类型

  • 48
  • 1
多克隆

标记

  • 25
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HIF3A antibody is un-conjugated

应用范围

  • 27
  • 19
  • 19
  • 14
  • 5
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 14
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-HIF3/HIF3A Antibody

    序列

    DDDFQLNASE QLPRAYHR

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by five amino acids.

    产品特性

    Anti-HIF3/HIF3A Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3, different from the related rat and mouse sequences by five amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Rat, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

    别名

    HIF3A

    背景

    Background: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

    Gene Full Name: hypoxia inducible factor 3 subunit alpha

    Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

    分子量

    49 kDa

    基因ID

    64344

    UniProt

    Q9Y2N7

    途径

    Warburg Effect
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