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SELENBP1 抗体 (Middle Region)

SELENBP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042829
发货至: 中国
  • 抗原 See all SELENBP1 抗体
    SELENBP1 (Selenium Binding Protein 1 (SELENBP1))
    抗原表位
    • 14
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 226-240, Middle Region
    适用
    • 49
    • 35
    • 29
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 45
    • 4
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SELENBP1 antibody is un-conjugated
    应用范围
    • 43
    • 18
    • 12
    • 12
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-SBP/SELENBP1 Antibody Picoband®
    序列
    SHLYVWDWQR HEIVQ
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-SBP/SELENBP1 Antibody (ABIN3042829). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human Selenium Binding Protein 1.
    亚型
    IgG
    Top Product
    Discover our top product SELENBP1 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Chang, P. W. G., Tsui, S. K. W., Liew, C., Lee, C., Waye, M. M. Y., Fung, K. Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein. J. Cell. Biochem. 64: 217-224, 1997. 2. Okunuki, Y., Usui, Y., Takeuchi, M., Kezuka, T., Hattori, T., Masuko, K., Nakamura, H., Yudoh, K., Usui, M., Nishioka, K., Kato, T. Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease. Exp. Eye Res. 84: 823-831, 2007.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SELENBP1 (Selenium Binding Protein 1 (SELENBP1))
    别名
    SELENBP1 (SELENBP1 产品)
    背景

    Synonyms: Selenium-binding protein 1,56 kDa selenium-binding protein,SBP56,SP56,SELENBP1,SBP,

    Tissue Specificity: Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. .

    Background: Selenium-binding protein 1, also known as SELENBP1 or SBP is a protein that in humans is encoded by the SLELNBP1 gene. This gene is mapped to 1q21.3. This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation.

    Sequence Similarities: Belongs to the PIAS family.

    分子量
    57 kDa
    UniProt
    Q13228
    途径
    Brown Fat Cell Differentiation
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