SERPINC1 抗体 (N-Term)
Quick Overview for SERPINC1 抗体 (N-Term) (ABIN3042828)
抗原
See all SERPINC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 93-107, N-Term
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原理
 - Anti-Antithrombin III/SERPINC1 Antibody Picoband®
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序列
 - TFYQHLADSK NDNDN
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交叉反应 (详细)
 - No cross-reactivity with other proteins
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产品特性
 - Anti-Antithrombin III/SERPINC1 Antibody (ABIN3042828). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III, different from the related mouse and rat sequences by one amino acid.
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Baud, O., Picard, V., Durand, P., Duchemin, J., Proulle, V., Albenc-Gelas, M., Devictor, D., Dreyfus, M. Intracerebral hemorrhage associated with a novel antithrombin gene mutation in a neonate. J. Pediat. 139: 741-743, 2001. 2. Fischer, A. M., Cornu, P., Sternberg, C., Meriane, F., Dautzenberg, M. D., Chafa, O., Beguin, S., Desnos, M. Antithrombin III Alger: a new homozygous AT III variant. Thromb. Haemost. 55: 218-221, 1986. - 
                                            
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
 - Thimerosal (Merthiolate), Sodium azide
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注意事项
 - This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
 - Avoid repeated freezing and thawing.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 
                                            
有效期
 - 12 months
 
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- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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别名
 - SERPINC1
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背景
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Synonyms: Antithrombin-III,ATIII,Serpin C1,SERPINC1,AT3,PRO0309,
Tissue Specificity: Found in plasma.
Background: Serpin peptidase inhibitor, clade C (antithrombin), member 1, also known as Antithrombin III (AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Sequence Similarities: Belongs to the serpin family.
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分子量
 - 57 kDa
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UniProt
 - P01008
 
抗原
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