CNN1 抗体 (C-Term)
(4 references)Quick Overview for CNN1 抗体 (C-Term) (ABIN3042824)
抗原
See all CNN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 283-297, C-Term
-
原理
- Anti-Calponin/CNN1 Antibody Picoband®
-
序列
- EPAHNHHAHN YYNSA
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Calponin/CNN1 Antibody (ABIN3042824). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Calponin, different from the related mouse and rat sequences by two amino acids.
-
亚型
- IgG
-
-
anti-Calponin 1 (CNN1) (AA 1-268) antibody
CNN1 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calponin 1 (CNN1) (AA 201-297) antibodyCNN1 适用: 人, 大鼠, 小鼠 FACS, WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calponin 1 (CNN1) antibodyCNN1 适用: 人, 大鼠 FACS, IF, IHC, StM 宿主: 兔 Monoclonal CNN1-1408R unconjugated Recombinant Antibody
anti-Calponin 1 (CNN1) antibodyCNN1 适用: 人, 大鼠 FACS, IF, IHC, WB, StM 宿主: 小鼠 Monoclonal CALP unconjugated
anti-Calponin 1 (CNN1) (AA 16-165) antibodyCNN1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1H5B5 unconjugated
anti-Calponin 1 (CNN1) antibodyCNN1 适用: 人, 大鼠 FACS, IHC, WB, StM 宿主: 小鼠 Monoclonal rCNN1-832 unconjugated Recombinant Antibody
anti-Calponin 1 (CNN1) (AA 10-39), (N-Term) antibodyCNN1 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB19472 unconjugated
anti-Calponin 1 (CNN1) (AA 1-297) antibodyCNN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F5-1H4 unconjugated
anti-Calponin 1 (CNN1) (C-Term) antibodyCNN1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-455R unconjugated Recombinant Antibody
anti-Calponin 1 (CNN1) antibodyCNN1 适用: 人 IHC, WB, ELISA 宿主: 兔 Monoclonal 2H1 unconjugated Recombinant Antibody
-
-
应用备注
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Miano, J. M., Krahe, R., Garcia, E., Elliott, J. M., Olson, E. N. Expression, genomic structure and high resolution mapping to 19p13.2 of the human smooth muscle cell calponin gene. Gene 197: 215-224, 1997. 2. Miano, J. M., Thomas, S., Disteche, C. M. Expression and chromosomal mapping of the mouse smooth muscle calponin gene. Mammalian Genome 12: 187-191, 2001. 3. Strasser, P., Gimona, M., Moessler, H., Herzog, M., Small, J. V. Mammalian calponin: identification and expression of genetic variants. FEBS Lett. 330: 13-18, 1993. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
-
: "Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells." in: Scientific reports, Vol. 6, pp. 30230, (2018) (PubMed).
: "Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of ..." in: PLoS ONE, Vol. 11, Issue 7, pp. e0157456, (2016) (PubMed).
: "Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes." in: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3957-65, (2015) (PubMed).
: "Bone morphogenic protein-2 regulates the myogenic differentiation of PMVECs in CBDL rat serum-induced pulmonary microvascular remodeling." in: Experimental cell research, Vol. 336, Issue 1, pp. 109-18, (2015) (PubMed).
-
: "Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells." in: Scientific reports, Vol. 6, pp. 30230, (2018) (PubMed).
-
- CNN1 (Calponin 1 (CNN1))
-
别名
- CNN1
-
背景
-
Synonyms: Calponin-1,Basic calponin,Calponin H1, smooth muscle,CNN1,
Tissue Specificity: Smooth muscle, and tissues containing significant amounts of smooth muscle.
Background: Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. This gene is mapped to 19p13.2. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is though to play a role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein though to be involved in some way in the regulation or modulation of contraction.
Sequence Similarities: Belongs to the calponin family.
-
分子量
- 33 kDa
-
UniProt
- P51911
抗原
-
