CD86 抗体 (AA 24-329)
Quick Overview for CD86 抗体 (AA 24-329) (ABIN3042788)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-329
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原理
- Anti-CD86 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CD86 Antibody Picoband® (ABIN3042788). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD86 recombinant protein (Position: A24-F329). Human CD86 shares 50% amino acid (aa) sequence identity with mouse CD86.
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亚型
- IgG
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anti-CD86 (CD86) (AA 140-175) antibody
CD86 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (fro), ICC, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) (AA 37-272) antibodyCD86 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, ELISA, BP, StM, Coat 宿主: 兔 Monoclonal C86-2160R unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, Func, BP, StM 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU63 unconjugated
anti-CD86 (CD86) antibody (FITC)CD86 适用: 人 FACS 宿主: 小鼠 Monoclonal BU63 FITC
anti-CD86 (CD86) (AA 30-247) antibodyCD86 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal rC86-1146 unconjugated Recombinant Antibody
anti-CD86 (CD86) antibodyCD86 适用: 人, 小鼠, 大鼠 WB, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal C86-1146 unconjugated
anti-CD86 (CD86) antibodyCD86 适用: 人 FACS, WB, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal BU63 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL
1. Chen C, Gault A, Shen L, Nabavi N (May 1994). "Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 Molecule". J. Immunol. 152 (10): 4929-36. 2. Reeves, R. H., Patch, D., Sharpe, A. H., Borriello, F., Freeman, G. J., Edelhoff, S., Disteche, C. The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3. Mammalian Genome 8: 581-582, 1997. 3. Shah, R., Banks, K., Patel, A., Dogra, S., Terrell, R., Powers, P. A., Fenton, C., Dinauer, C. A., Tuttle, R. M., Francis, G. L. Intense expression of the B7-2 antigen presentation coactivator is an unfavorable prognostic indicator for differentiated thyroid carcinoma of children and adolescents. J. Clin. Endocr. Metab. 87: 4391-4397, 2002. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD86
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别名
- CD86
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背景
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Synonyms: T-lymphocyte activation antigen CD86,Activation B7-2 antigen,B70,BU63,CTLA-4 counter-receptor B7.2,FUN-1,CD86,CD86,CD28LG2,
Tissue Specificity: Expressed by activated B-lymphocytes and monocytes.
Background: Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.
Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
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分子量
- 60-80 kDa
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基因ID
- 942
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UniProt
- P42081
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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