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CXCL10 抗体 (AA 22-98)

This anti-CXCL10 antibody is a 兔 多克隆 antibody detecting CXCL10 in WB, ELISA 和 IHC. Suitable for 小鼠.
产品编号 ABIN3042779
发货至: 中国

Quick Overview for CXCL10 抗体 (AA 22-98) (ABIN3042779)

抗原

See all CXCL10 抗体
CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

适用

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小鼠

宿主

  • 120
  • 36
  • 3
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  • 2
  • 1
  • 1

克隆类型

  • 116
  • 49
多克隆

标记

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This CXCL10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 35
    • 16
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    AA 22-98

    原理

    Anti-IP10/CXCL10 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-IP10/CXCL10 Antibody Picoband® (ABIN3042779). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse IP10 recombinant protein (Position: I22-P98). Mouse IP10 shares 70.1% and 77.9% amino acid (aa) sequence identity with human and rat IP10, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    Immunohistochemistry, 2-5 μg/mL, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Feferman, T., Maiti, P. K., Berrih-Aknin, S., Bismuth, J., Bidault, J., Fuchs, S., Souroujon, M. C.Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis.J. Immun.174: 5324-5331, 2005. 2. Luster AD, Unkeless JC, Ravetch JV (1985). "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins". Nature 315 (6021): 672-6. 3. Luster AD, Jhanwar SC, Chaganti RS, Kersey JH, Ravetch JV (May 1987). "Interferon-inducible gene maps to a chromosomal band associated with a (4,11) translocation in acute leukemia cells". Proc. Natl. Acad. Sci. U.S.A. 84 (9): 2868-71.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

    别名

    Cxcl10

    背景

    Synonyms: C-X-C motif chemokine 10,10 kDa interferon gamma-induced protein,Gamma-IP10,IP-10,C7,Interferon-gamma induced protein CRG-2,Small-inducible cytokine B10,Cxcl10,Crg2, Ifi10, Inp10, Scyb10,

    Tissue Specificity: Expressed in the spleen, thymus, lymph nodes and liver. .

    Background: C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10 kDa (IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al. (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10 (IP-10, CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.

    分子量

    19 kDa

    基因ID

    15945

    UniProt

    P17515
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