Cathepsin D 抗体 (AA 65-410)
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- 抗原 See all Cathepsin D (CTSD) 抗体
- Cathepsin D (CTSD)
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抗原表位
- AA 65-410
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cathepsin D antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC-P in Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: cathepsin D
Protein Name: Cathepsin D - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived mouse Cathepsin D recombinant protein (Position: E65-L410). Mouse Cathepsin D shares 85% and 91% amino acid (aa) sequences identity with human and rat Cathepsin D, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CTSD Primary Antibody
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anti-Cathepsin D (CTSD) (C-Term) antibody
CTSD 适用: 人, 小鼠, 大鼠, Hamster, 猴, Pig, 犬, Cow, 豚鼠, 马, 兔, Cat, Avian, 小鸡, 驴, 山羊, 绵羊 WB, IHC (p), IF, IHC (fro), IEM 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 66-410) antibodyCTSD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 1-412) antibodyCTSD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSD-3082 unconjugated
anti-Cathepsin D (CTSD) (AA 26-412) antibodyCTSD 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 3F12-1B9 unconjugated
anti-Cathepsin D (CTSD) (AA 21-412) antibodyCTSD 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Cathepsin D (CTSD) (AA 120-407) antibodyCTSD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CTSD-3276 unconjugated
anti-Cathepsin D (CTSD) (C-Term) antibodyCTSD 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 101-200) antibodyCTSD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for Cathepsin D is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).
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: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).
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- 抗原
- Cathepsin D (CTSD)
- 别名
- CTSD (CTSD 产品)
- 别名
- catD antibody, fb93e11 antibody, fj17b09 antibody, wu:fb93e11 antibody, wu:fj17b09 antibody, LOC398557 antibody, Cathd antibody, CatD antibody, LOC100136761 antibody, CTSD antibody, DKFZp469J0315 antibody, DDBDRAFT_0205785 antibody, DDBDRAFT_0215012 antibody, DDB_0205785 antibody, DDB_0215012 antibody, CLN10 antibody, CPSD antibody, CD antibody, cathepsin D antibody, cathepsin D S homeolog antibody, lysosomal aspartic protease antibody, cathepsin D-like antibody, ctsd antibody, LOC398557 antibody, ctsd.S antibody, CatD antibody, LOC5567565 antibody, LOC100136761 antibody, CTSD antibody, Cathd antibody, ctsD antibody, catd antibody, Ctsd antibody, LOC443060 antibody
- 背景
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Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.
Synonyms: CatD antibody|CATD_HUMAN antibody|Cathepsin D heavy chain antibody|Cathepsin D light chain antibody|CathepsinD antibody|CD antibody|Ceroid lipofuscinosis neuronal 10 antibody|CLN10 antibody|CPSD antibody|CTSD antibody|Lysosomal aspartyl peptidase antibody|Lysosomal aspartyl protease antibody|MGC2311 antibody - 基因ID
- 13033
- UniProt
- P18242
- 途径
- Peptide Hormone Metabolism
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