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Cathepsin D 抗体 (AA 65-410)

This anti-Cathepsin D antibody is a 兔 多克隆 antibody detecting Cathepsin D in WB, IHC, ICC 和 IF. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
Pubmed (1 reference)
产品编号 ABIN3042775
发货至: 中国

Quick Overview for Cathepsin D 抗体 (AA 65-410) (ABIN3042775)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Cathepsin D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Discover our top product CTSD Primary Antibody

  • 抗原表位

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    AA 65-410

    原理

    Anti-Cathepsin D/CTSD Antibody Picoband®

    交叉反应 （详细）

    No cross-reactivity with other proteins

    产品特性

    Anti-Cathepsin D/CTSD Antibody Picoband® (ABIN3042775). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Cathepsin D recombinant protein (Position: E65-L410). Mouse Cathepsin D shares 85% and 91% amino acid (aa) sequences identity with human and rat Cathepsin D, respectively.

    亚型

    IgG
  • anti-Cathepsin D (CTSD) (C-Term) antibody
    anti-Cathepsin D (CTSD) (C-Term) antibody

    CTSD 适用: 人, 小鼠, 大鼠, Hamster, 猴, Cow, 兔, Pig, 犬, 豚鼠, 马, Avian, Cat, 小鸡, 驴, 山羊, 绵羊 WB, IHC (p), IF, IHC (fro), IEM 宿主: 山羊 Polyclonal unconjugated

    anti-Cathepsin D (CTSD) (AA 66-410) antibody
    anti-Cathepsin D (CTSD) (AA 66-410) antibody

    CTSD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Cathepsin D (CTSD) (AA 1-412) antibody
    anti-Cathepsin D (CTSD) (AA 1-412) antibody

    CTSD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

    anti-Cathepsin D (CTSD) (AA 26-412) antibody
    anti-Cathepsin D (CTSD) (AA 26-412) antibody

    CTSD 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B9 unconjugated

    anti-Cathepsin D (CTSD) (AA 104-250) antibody
    anti-Cathepsin D (CTSD) (AA 104-250) antibody

    CTSD 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSD-3082 unconjugated

    anti-Cathepsin D (CTSD) (AA 21-412) antibody
    anti-Cathepsin D (CTSD) (AA 21-412) antibody

    CTSD 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated

    anti-Cathepsin D (CTSD) (AA 120-407) antibody
    anti-Cathepsin D (CTSD) (AA 120-407) antibody

    CTSD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Cathepsin D (CTSD) (AA 104-250) antibody
    anti-Cathepsin D (CTSD) (AA 104-250) antibody

    CTSD 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CTSD-3276 unconjugated

    anti-Cathepsin D (CTSD) (C-Term) antibody
    anti-Cathepsin D (CTSD) (C-Term) antibody

    CTSD 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

    anti-Cathepsin D (CTSD) (AA 101-200) antibody
    anti-Cathepsin D (CTSD) (AA 101-200) antibody

    CTSD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Mouse
    1. Faust PL, Kornfeld S, Chirgwin JM (Sep 1985). "Cloning and sequence analysis of cDNA for human cathepsin D". Proc Natl Acad Sci U S A 82 (15): 4910-4. 2. Wolf M, Clark-Lewis I, Buri C, Langen H, Lis M, Mazzucchelli L (April 2003). "Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer". Am. J. Pathol. 162 (4): 1183-90.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用

  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Zheng, Li, Wang, Wang, Liao, Hu, Fan, Kang, Zeng, Wu, Wu, Zhang, Wang, He et al.: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).

  • 抗原

    Cathepsin D (CTSD)

    别名

    CTSD

    背景

    Synonyms: Cathepsin D,3.4.23.5,Ctsd,

    Tissue Specificity: Expressed in the aorta extrcellular space (at protein level). .

    Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

    Sequence Similarities: Belongs to the peptidase A1 family.

    分子量

    45 kDa

    基因ID

    13033

    UniProt

    P18242

    途径

    Peptide Hormone Metabolism
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