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CTGF 抗体 (AA 58-349)

CTGF 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042771
发货至: 中国
  • 抗原 See all CTGF 抗体
    CTGF (Connective Tissue Growth Factor (CTGF))
    抗原表位
    • 16
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-349
    适用
    • 123
    • 65
    • 48
    • 4
    • 3
    • 2
    • 2
    • 2
    人, 大鼠
    宿主
    • 118
    • 32
    • 3
    • 2
    克隆类型
    • 122
    • 33
    多克隆
    标记
    • 70
    • 28
    • 19
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTGF antibody is un-conjugated
    应用范围
    • 122
    • 71
    • 54
    • 22
    • 20
    • 18
    • 18
    • 15
    • 13
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Connective tissue growth factor(CTGF) detection. Tested with WB, IHC-P in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Connective tissue growth factor(CTGF) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: connective tissue growth factor
    Protein Name: Connective tissue growth factor
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.
    亚型
    IgG
    Top Product
    Discover our top product CTGF Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Lu, Kang, Hu, Tang, Zhou, Yu, Xu: "Angiotensin-(1-7) relieved renal injury induced by chronic intermittent hypoxia in rats by reducing inflammation, oxidative stress and fibrosis." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 1, pp. e5594, (2017) (PubMed).

    Lv, Wu, Li, Wang, Wang, Zhang, Xu, Zhang: "Effect of QiShenYiQi pill on myocardial collagen metabolism in experimental autoimmune myocarditis rats." in: Biomedicine & pharmacotherapy, Vol. 88, pp. 894-901, (2017) (PubMed).

    Zhang, Li, Zheng, Lin, Zhang, Zhang: "Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis." in: Oncotarget, Vol. 8, Issue 43, pp. 73529-73546, (2017) (PubMed).

    Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

    Bai, Li, Zhao, Liu, Wang, Lian, Zhao, Wang: "PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor." in: Oncotarget, Vol. 8, Issue 67, pp. 111642-111655, (2017) (PubMed).

    Cheng, Xiao, Ainiwaer, Wang, Wu, Mao, Yang, Bao: "Molecular responses of radiation-induced liver damage in rats." in: Molecular medicine reports, Vol. 11, Issue 4, pp. 2592-600, (2015) (PubMed).

    Ma, Li, Yue, Guo, Xu, Xu, Jia, Yu, Zhang, Liu, Liu, Shao, Chen, Liu: "Cryptotanshinone attenuates cardiac fibrosis via downregulation of COX-2, NOX-2, and NOX-4." in: Journal of cardiovascular pharmacology, Vol. 64, Issue 1, pp. 28-37, (2014) (PubMed).

    Jin, Shi, Zou, Miao, Sun, Li: "Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 259368, (2014) (PubMed).

    Wang, Zhuang, Gao, Zhang, Yang: "Increased expression of CCN2 in the red flashing light-induced myopia in guinea pigs." in: BioMed research international, Vol. 2013, pp. 761823, (2014) (PubMed).

    Guo, Qi, Yu, Du, Wu, Liu: "Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats." in: Diabetology & metabolic syndrome, Vol. 6, Issue 1, pp. 29, (2014) (PubMed).

    Li, Dai, Zhao, Zhang, Hui, Zhang, Jin: "Preventative effect of Astragalus flavescens on hepatic fibrosis in rats and its mechanism of action." in: Experimental and therapeutic medicine, Vol. 6, Issue 4, pp. 904-908, (2013) (PubMed).

    Wang, Li, Lu, Zhao, Xu: "Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats." in: Croatian medical journal, Vol. 54, Issue 2, pp. 171-9, (2013) (PubMed).

    Wen, Huang, Zhang, Zhang, Chen, Gu, Hao: "Resveratrol attenuates diabetic nephropathy via modulating angiogenesis." in: PLoS ONE, Vol. 8, Issue 12, pp. e82336, (2013) (PubMed).

    Li, Zhang, Wang, Zheng, Chen: "Nicousamide blocks the effects of advanced glycation end products on renal cells." in: European journal of pharmacology, Vol. 674, Issue 2-3, pp. 455-9, (2012) (PubMed).

    Wang, Li, Lu, Zhao: "Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy." in: Heart international, Vol. 6, Issue 2, pp. e21, (2012) (PubMed).

    Wang, Hui, Fan, Xiong, Sun: "Filtering bleb area and intraocular pressure following subconjunctival injection of CTGF antibody after glaucoma filtration surgery in rabbits." in: International journal of ophthalmology, Vol. 4, Issue 5, pp. 480-3, (2012) (PubMed).

    Wang, Li, Lu, Bao, Zhao: "Luteolin ameliorates cardiac failure in type I diabetic cardiomyopathy." in: Journal of diabetes and its complications, Vol. 26, Issue 4, pp. 259-65, (2012) (PubMed).

    Guo, Zhang, Li, Xu: "Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats." in: Cardiovascular diabetology, Vol. 11, pp. 94, (2012) (PubMed).

  • 抗原
    CTGF (Connective Tissue Growth Factor (CTGF))
    别名
    CTGF (CTGF 产品)
    别名
    Ccn2 antibody, Fisp12 antibody, Hcs24 antibody, fisp-12 antibody, CCN2 antibody, HCS24 antibody, IGFBP8 antibody, NOV2 antibody, CTGRP antibody, ctgf antibody, hm:zeh1559 antibody, si:dkey-266k12.4 antibody, wu:fl25c03 antibody, zeh1559 antibody, zgc:136644 antibody, XCTGF antibody, ccn2 antibody, nov2 antibody, hcs24 antibody, igfbp8 antibody, CTGF antibody, si:ch211-173b8.2 antibody, connective tissue growth factor antibody, connective tissue growth factor a antibody, connective tissue growth factor L homeolog antibody, connective tissue growth factor b antibody, Ctgf antibody, CTGF antibody, ctgfa antibody, ctgf.L antibody, ctgf antibody, ctgfb antibody
    背景
    CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

    Synonyms: CCN 2 antibody|CCN family member 2 antibody|CCN2 antibody|Connective Tissue Growth Factor antibody|CTGF antibody|CTGF_HUMAN antibody|Hcs 24 antibody|Hcs24 antibody|Hypertrophic chondrocyte specific protein 24 antibody|Hypertrophic chondrocyte-specific gene product 24 antibody|Hypertrophic chondrocyte-specific protein 24 antibody|IBP-8 antibody|IGF-binding protein 8 antibody|IGFBP-8 antibody|IGFBP8 antibody|Insulin like Growth Factor Binding Protein 8 antibody|Insulin-like Growth Factor-Binding Protein 8 antibody|MGC102839 antibody|NOV 2 antibody|NOV2 antibody
    基因ID
    1490
    UniProt
    P29279
    途径
    Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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