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CTH 抗体 (AA 181-398)

Cited in 5+ publications. This 兔 多克隆 anti-CTH antibody specifically detects CTH in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN3042770
发货至: 中国
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Quick Overview for CTH 抗体 (AA 181-398) (ABIN3042770)

抗原

See all CTH 抗体
CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

适用

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人, 小鼠, 大鼠

宿主

  • 65
  • 13

克隆类型

  • 53
  • 25
多克隆

标记

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This CTH antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 16
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    AA 181-398

    原理

    Anti-Cystathionase/CTH Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Cystathionase/CTH Antibody (ABIN3042770). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cystathionase recombinant protein (Position: D181-H398). Human Cystathionase shares 85.8% amino acid (aa) sequence identity with both mouse and rat Cystathionase.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

    Qi, Zhao, Li, Shao, Wang, Sui, Yu, Shao, Gui, Li, Jia, Jiang, Li, Zhang, Wang, Wang: "High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways." in: International journal of oncology, Vol. 53, Issue 1, pp. 358-370, (2018) (PubMed).

    Shi, Guo, Shi, Yu, Song, Li: "Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2774-80, (2016) (PubMed).

    Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

    Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).

  • 抗原

    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

    别名

    CTH

    背景

    Synonyms: Cystathionine gamma-lyase,4.4.1.1,Cysteine-protein sulfhydrase,Gamma-cystathionase,CTH,

    Tissue Specificity: Ubiquitous. Absent in primary spermatocytes. .

    Background: Cystathionine gamma-lyase (or cystathionase) is an enzyme which breaks down cystathionine into cysteine and α-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide (H2S) is physiologically generated by CTH.

    Sequence Similarities: Belongs to the CTCF zinc-finger protein family.

    分子量

    45 kDa

    基因ID

    10664

    UniProt

    P32929

    途径

    ER-Nucleus Signaling, Warburg Effect
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