CSTA 抗体 (AA 8-98)
Quick Overview for CSTA 抗体 (AA 8-98) (ABIN3042766)
抗原
See all CSTA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-98
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原理
- Anti-Cystatin A/CSTA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cystatin A/CSTA Antibody Picoband® (ABIN3042766). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cystatin A recombinant protein (Position: E8-F98). Human Cystatin A shares 61.5% and 58.2% amino acid (aa) sequence identity with mouse and rat Cystatin A, respectively.
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亚型
- IgG
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anti-Cystatin A (Stefin A) (CSTA) antibody
CSTA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-CSTA-1 unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 2-98) antibodyCSTA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystatin A (Stefin A) (CSTA) (C-Term) antibodyCSTA 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cystatin A (Stefin A) (CSTA) (C-Term) antibodyCSTA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 1-98) antibodyCSTA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CSTA-2882 unconjugated
anti-Cystatin A (Stefin A) (CSTA) antibodyCSTA 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-461M unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 1-98) antibodyCSTA 适用: 人 WB, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 1-98) antibodyCSTA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 1-98) antibodyCSTA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Cystatin A (Stefin A) (CSTA) (AA 1-98) antibodyCSTA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
1. Blaydon, D. C., Nitoiu, D., Eckl, K.-M., Cabral, R. M., Bland, P., Hausser, I., van Heel, D. A., Rajpopat, S., Fischer, J., Oji, V., Zvulunov, A., Traupe, H., Hennies, H. C., Kelsell, D. P. Mutations in CSTA, encoding cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am. J. Hum. Genet. 89: 564-571, 2011. 2. Samuelsson, L., Stiller, C., Friberg, C., Nilsson, C., Inerot, A., Wahlstrom, J.Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J. Invest. Derm. 122: 1399-1400, 2004. 3. Vasilopoulos, Y., Walters, J., Cork, M. J., Duff, G. W., Sagoo, G. S., Tazi-Ahnini, R.Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.Europ. J. Hum. Genet. 16: 1002-1009, 2008. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CSTA (Cystatin A (Stefin A) (CSTA))
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别名
- CSTA
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背景
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Synonyms: Cystatin-A,Cystatin-AS,Stefin-A,Cystatin-A, N-terminally processed,CSTA,STF1, STFA,
Tissue Specificity: Expressed in the skin throughout the epidermis. .
Background: Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer.
Sequence Similarities: Belongs to the cystatin family.
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分子量
- 14 kDa
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基因ID
- 1475
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UniProt
- P01040
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途径
- Response to Water Deprivation
抗原
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