CRY1 抗体 (N-Term)
Quick Overview for CRY1 抗体 (N-Term) (ABIN3042761)
抗原
See all CRY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 153-189, N-Term
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原理
- Anti-Cryptochrome I/CRY1 Antibody Picoband®
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序列
- FQTLISKMEP LEIPVETITS EVIEKCTTPL SDDHDEK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cryptochrome I/CRY1 Antibody Picoband® (ABIN3042761). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Cryptochrome I, different from the related mouse sequence by seven amino acids, and from the related rat sequence by six amino acids.
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亚型
- IgG
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anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-586) antibody
CRY1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 3-132) antibodyCRY1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) antibodyCRY1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 小鸡 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 507-586) antibodyCRY1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-587) antibodyCRY1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-586) antibodyCRY1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-255) antibodyCRY1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 556-586), (C-Term) antibodyCRY1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1844 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) antibodyCRY1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 151-200) antibodyCRY1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 马, 绵羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human1. Griffin EA, Staknis D, Weitz CJ (October 1999). "Light-independent role of CRY1 and CRY2 in the mammalian circadian clock". Science 286 (5440): 768-71. 2. Ukai-Tadenuma M, Yamada RG, Xu H, Ripperger JA, Liu AC, Ueda HR (Jan 2011). "Delay in feedback repression by cryptochrome 1 is required for circadian clock function". Cell 144 (2): 268-81. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
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别名
- CRY1
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背景
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Synonyms: Cryptochrome-1,CRY1,PHLL1,
Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.
Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. And this gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
Sequence Similarities: Belongs to the DNA photolyase class-1 family.
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分子量
- 66 kDa
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基因ID
- 1407
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UniProt
- Q16526
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途径
- Response to Water Deprivation, Proton Transport
抗原
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