CRY2 抗体 (N-Term)
Quick Overview for CRY2 抗体 (N-Term) (ABIN3042760)
抗原
See all CRY2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-200, N-Term
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原理
- Anti-CRY2 Antibody Picoband®
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序列
- RFQAIISRME LPKKPVGLVT SQQMESCRAE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CRY2 Antibody Picoband® (ABIN3042760). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CRY2, different from the related mouse and rat sequences by five amino acids.
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亚型
- IgG
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anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 141-231) antibody
CRY2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 564-593), (C-Term) antibodyCRY2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1846 unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 434-593) antibodyCRY2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 1-593) antibodyCRY2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (N-Term) antibodyCRY2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) antibodyCRY2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1819CT334-92-36-9 unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 179-228) antibodyCRY2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 455-614) antibodyCRY2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (C-Term) antibodyCRY2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Kovanen L, Kaunisto M, Donner K, Saarikoski ST, Partonen T. ""CRY2 genetic variants associate with dysthymia."" PLoS One, 2013. 2. Mao Y, Fu A, Hoffman AE, Jacobs DI, Jin M, Chen K, Zhu Y. ""The circadian gene CRY2 is associated with breast cancer aggressiveness possibly via epigenomic modifications."" Tumour Biol, 2015 May. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))
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别名
- CRY2
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背景
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Synonyms: Cryptochrome-2,CRY2,KIAA0658,
Tissue Specificity: Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle. .
Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. And it is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Belongs to the DNA photolyase class-1 family.
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分子量
- 67 kDa
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基因ID
- 1408
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途径
- Response to Water Deprivation, Protein targeting to Nucleus
抗原
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