CREB3L1 抗体 (AA 1-204)
Quick Overview for CREB3L1 抗体 (AA 1-204) (ABIN3042759)
抗原
See all CREB3L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-204
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原理
- Anti-CREB3L1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-CREB3L1 Antibody Picoband® (ABIN3042759). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CREB3L1 recombinant protein (Position: M1-M204). Human CREB3L1 shares 93.6% and 93.1% amino acid (aa) sequence identity with mouse and rat CREB3L1, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Denard B, Lee C, Ye J. ""Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1"". Elife, 2012 Dec 18. 2. Mellor P, Deibert L, Calvert B, Bonham K, Carlsen SA, Anderson DH. ""CREB3L1 is a metastasis suppressor that represses expression of genes regulating metastasis, invasion, and angiogenesis"". Mol Cell Biol, 2013 Dec. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
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别名
- CREB3L1
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背景
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Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1,cAMP-responsive element-binding protein 3-like protein 1,Old astrocyte specifically-induced substance,OASIS,Processed cyclic AMP-responsive element-binding protein 3-like protein 1,CREB3L1,OASIS,PSEC0238,
Tissue Specificity: Expressed in several tissues, with highest levels in pancreas and prostate. Expressed at relatively lower levels in brain. .
Background: CREB3L1, known as Cyclic AMP-responsive element-binding protein 3-like protein 1, is mapped to 11p11.2. The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements.
Sequence Similarities: Belongs to the bZIP family. ATF subfamily.
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分子量
- 57 kDa
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基因ID
- 90993
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途径
- Thyroid Hormone Synthesis, Chromatin Binding
抗原
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