CPT1B 抗体 (N-Term)
Quick Overview for CPT1B 抗体 (N-Term) (ABIN3042757)
抗原
See all CPT1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 197-226, N-Term
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原理
- Anti-CPT1B Antibody Picoband®
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序列
- DDEEYYRMEL LAKEFQDKTA PRLQKYLVLK
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-CPT1B Antibody Picoband® (ABIN3042757). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CPT1B, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunofluorescence, 5 μg/mL1. Auinger A, Rubin D, Sabandal M, Helwig U, Rüther A, Schreiber S, Foelsch UR, Döring F, Schrezenmeir J. ""A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome"". Br J Nutr, 2013 Mar 14. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
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别名
- CPT1B
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背景
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Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform,CPT1-M,2.3.1.21,Carnitine O-palmitoyltransferase I, muscle isoform,CPT I,CPTI-M,Carnitine palmitoyltransferase 1B,Carnitine palmitoyltransferase I-like protein,CPT1B,KIAA1670,
Tissue Specificity: Strong expression in heart and skeletal muscle. No expression in liver and kidney.
Background: CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
Sequence Similarities: Belongs to the carnitine/choline acetyltransferase family.
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分子量
- 88 kDa
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基因ID
- 1375
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UniProt
- Q92523
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途径
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
抗原
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