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CX3CL1 抗体 (N-Term)

This anti-CX3CL1 antibody is a 兔 多克隆 antibody detecting CX3CL1 in WB 和 IHC. Suitable for 大鼠 和 小鼠.
产品编号 ABIN3042714
发货至: 中国

Quick Overview for CX3CL1 抗体 (N-Term) (ABIN3042714)

抗原

See all CX3CL1 抗体
CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

适用

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大鼠, 小鼠

宿主

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克隆类型

  • 92
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多克隆

标记

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This CX3CL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 74-92, N-Term

    原理

    Anti-Fractalkine CX3CL1 Antibody Picoband®

    序列

    CADPKEKWVQ DAMKHLDHQ

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Fractalkine CX3CL1 Antibody (ABIN3042714). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of mouse CX3CL1, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat, -
    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    1. Pan et al., Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M et al. (1997). "Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation". Nature 387 (6633): 611-617. doi:10.1038/42491. PMID 9177350. 2. Bazan et al., Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A et al. (1997). "A new class of membrane-bound chemokine with a CX3C motif". Nature 385 (6617): 640-644. doi:10.1038/385640a0. PMID 9024663. 3. Hannan, N. J., Jones, R. L., Critchley, H. O. D., Kovacs, G. J., Rogers, P. A. W., Affandi, B., Salamonsen, L. A.Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role of fractalkine in leukocyte recruitment and endometrial remodeling.J. Clin. Endocr. Metab.89: 6119-6129, 2004.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

    别名

    CX3CL1

    背景

    Synonyms: Fractalkine,C-X3-C motif chemokine 1,CX3C membrane-anchored chemokine,Neurotactin,Small-inducible cytokine D1,Processed fractalkine,Cx3cl1,Cx3c, Fkn, Scyd1,

    Tissue Specificity: Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.

    Background: Chemokine (C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al. (1997) identified a 7-transmembrane high-affinity receptor (CX3CR1, 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.

    分子量

    90-100 kDa

    UniProt

    O35188

    途径

    Synaptic Membrane
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