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ANGPTL4 抗体 (C-Term)

This anti-ANGPTL4 antibody is a 兔 多克隆 antibody detecting ANGPTL4 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN3042686
发货至: 中国

Quick Overview for ANGPTL4 抗体 (C-Term) (ABIN3042686)

抗原

See all ANGPTL4 抗体
ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

适用

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  • 1
人, 大鼠

宿主

  • 68
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  • 1

克隆类型

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  • 16
多克隆

标记

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  • 1
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This ANGPTL4 antibody is un-conjugated

应用范围

  • 71
  • 40
  • 33
  • 19
  • 14
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

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    • 2
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    • 1
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    • 1
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    • 1
    • 1
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    AA 349-367, C-Term

    原理

    Anti-Angiopoietin-like 4/ANGPTL4 Antibody Picoband®

    序列

    WWFGTCSHSN LNGQYFRSI

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Angiopoietin-like 4/ANGPTL4 Antibody (ABIN3042686). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin-like 4, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Romeo, S., Pennacchio, L. A., Fu, Y., Boerwinkle, E., Tybjaerg-Hansen, A., Hobbs, H. H., Cohen, J. C.Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nature Genet. 39: 513-516, 2007. 2. Yoon, J. C., Chickering, T. W., Rosen, E. D., Dussault, B., Qin, Y., Soukas, A., Friedman, J. M., Holmes, W. E., Spiegelman, B. M.Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Molec. Cell. Biol. 20: 5343-5349, 2000.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

    别名

    ANGPTL4

    背景

    Synonyms: Angiopoietin-related protein 4,Angiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ANGPTL4,ARP4, HFARP, PGAR,PP1158, PSEC0166, UNQ171/PRO197,

    Tissue Specificity: Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney. .

    Background: Angiopoietin-related protein 4 (Angptl4) is a protein that in humans is encoded by the ANGPTL4 gene. This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. By radiation hybrid analysis, Angptl4 gene is mapped to 19p13.3. ANGPTL4 contributed to tumor growth and protected cells from anoikis, a form of programmed cell death induced when contact-dependent cells detach from the surrounding tissue matrix.

    Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

    分子量

    45 kDa

    途径

    Regulation of Lipid Metabolism by PPARalpha
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