Caveolin 2 抗体 (N-Term)
(1 reference)Quick Overview for Caveolin 2 抗体 (N-Term) (ABIN3042683)
抗原
See all Caveolin 2 (CAV2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-17, N-Term
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原理
- Anti-Caveolin-2/CAV2 Antibody Picoband®
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序列
- MGLETEKADV QLFMDDD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Caveolin-2/CAV2 Antibody (ABIN3042683). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-Caveolin 2 (CAV2) (N-Term) antibody
CAV2 适用: 人 WB, IHC (p), IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-86) antibodyCAV2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5E9E2 unconjugated
anti-Caveolin 2 (CAV2) (N-Term) antibodyCAV2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 猴, 马, Pig, Hamster, 山羊, 驴, 小鸡, Cat, Avian WB, IHC (p), IF, IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-17) antibodyCAV2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 3-64) antibodyCAV2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) antibodyCAV2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-162) antibodyCAV2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 11-44), (N-Term) antibodyCAV2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB16483 unconjugated
anti-Caveolin 2 (CAV2) (N-Term) antibodyCAV2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) antibodyCAV2 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Scherer, P. E., Okamoto, T., Chun, M., Nishimoto, I., Lodish, H. F., Lisanti, M. P.Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.Proc. Nat. Acad. Sci. 93: 131-135, 1996. 2. Yamazaki, K., Mizui, Y., Tanaka, I.Radiation hybrid mapping of human ADAM10 gene to chromosome 15.Genomics 45: 457-459, 1997. 2. Galbiati, F., Volonte, D., Gil, O., Zanazzi, G., Salzer, J. L., Sargiacomo, M., Scherer, P. E., Engelman, J. A., Schlegel, A., Parenti, M., Okamoto, T., Lisanti, M. P.Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury.Proc. Nat. Acad. Sci. 95: 10257-10262, 1998. 3. Engelman, J. A., Zhang, X. L., Galbiati, F., Lisanti, M. P.Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3): Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).FEBS Lett. 429: 330-336, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
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: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
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- Caveolin 2 (CAV2)
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别名
- CAV2
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背景
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Synonyms: Caveolin-2,CAV2,
Tissue Specificity: Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .
Background: Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Caveolin-1 and caveolin-2 are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.
Sequence Similarities: Belongs to the caveolin family.
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分子量
- 17 kDa
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UniProt
- P51636
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
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