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CDK5 抗体 (C-Term)

CDK5 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042679
发货至: 中国
  • 抗原 See all CDK5 抗体
    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
    抗原表位
    • 30
    • 16
    • 16
    • 11
    • 10
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 273-292, C-Term
    适用
    • 123
    • 101
    • 97
    • 13
    • 12
    • 11
    • 11
    • 11
    • 11
    • 9
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    • 8
    • 4
    • 3
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    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 111
    • 28
    克隆类型
    • 112
    • 27
    多克隆
    标记
    • 70
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This CDK5 antibody is un-conjugated
    应用范围
    • 118
    • 39
    • 39
    • 39
    • 39
    • 21
    • 20
    • 19
    • 18
    • 10
    • 10
    • 4
    • 3
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Cyclin-dependent-like kinase 5(CDK5) detection. Tested with WB in Human,Mouse,Rat.
    序列
    QRISAEEALQ HPYFSDFCPP
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Cyclin-dependent-like kinase 5(CDK5) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: cyclin-dependent kinase 5
    Protein Name: Cyclin-dependent-like kinase 5
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk5(273-292aa QRISAEEALQHPYFSDFCPP), identical to the related rat and mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product CDK5 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Li, Zhang, Zhu, Zhang, Lin, Xu, Yang, Hao, Zhang: "A new treatment for cognitive disorders related to in utero exposure to alcohol." in: Neural regeneration research, Vol. 8, Issue 18, pp. 1702-13, (2014) (PubMed).

  • 抗原
    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
    别名
    CDK5 (CDK5 产品)
    别名
    PSSALRE antibody, AW048668 antibody, Crk6 antibody, CDK5 antibody, CG8203 antibody, DmCdk5 antibody, Dmel\\CG8203 antibody, cdk5 antibody, zgc:101604 antibody, cyclin dependent kinase 5 antibody, cyclin-dependent kinase 5 antibody, Cyclin-dependent kinase 5 antibody, cyclin-dependent kinase 5 L homeolog antibody, Cyclin-dependent-like kinase 5 antibody, CDK5 antibody, Cdk5 antibody, cdk5 antibody, cdk5.L antibody, cdk-5 antibody
    背景
    CDK5, Cyclin-Dependent Kinase5, is also know as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35(CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

    Synonyms: Cdk 5 antibody|Cdk5 antibody|CDK5_HUMAN antibody|Cell division protein kinase 5 antibody|Crk6 antibody|Cyclin dependent kinase 5 antibody|Cyclin-dependent kinase 5 antibody|Protein kinase CDK5 splicing antibody|PSSALRE antibody|Serine threonine protein kinase PSSALRE antibody|Serine/threonine-protein kinase PSSALRE antibody|Tau protein kinaseII catalytic subunit antibody|TPKII catalytic subunit antibody
    UniProt
    Q00535
    途径
    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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