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CDK5 抗体 (C-Term)

Name: CDK5 抗体 (C-Term)
SKU: ABIN3042679
Availability: OutOfStock

This anti-CDK5 antibody is a 兔多克隆 antibody detecting CDK5 in WB. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Anti-Cdk5 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell Lysate (CDK5 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN3042679

发货至: 中国

Quick Overview for CDK5 抗体 (C-Term) (ABIN3042679)

抗原

See all CDK5 抗体

CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CDK5 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CDK5 Primary Antibody

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AA 273-292, C-Term

原理

Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody Picoband®

序列

QRISAEEALQ HPYFSDFCPP

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody (ABIN3042679). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk5, identical to the related rat and mouse sequence.

亚型

IgG
anti-Cyclin-Dependent Kinase 5 (CDK5) antibody
CDK5 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4E4 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 15-100) antibody
CDK5 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) antibody
CDK5 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1552CT262-105-8 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289) antibody
CDK5 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (Tyr15) antibody
CDK5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289), (C-Term) antibody
CDK5 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB50850 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Demetrick, D. J., Zhang, H., Beach, D. H.Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.Cytogenet. Cell Genet. 66: 72-74, 1994. 2. Ohshima, T., Nagle, J. W., Pant, H. C., Joshi, J. B., Kozak, C. A., Brady, R. O., Kulkarni, A. B.Molecular cloning and chromosomal mapping of the mouse cyclin-dependent kinase 5 gene.Genomics 28: 585-588, 1995. 3. Bibb, J. A., Snyder, G. L., Nishi, A., Yan, Z., Meijer, L., Fienberg, A. A., Tsai, L.-H., Kwon, Y. T., Girault, J.-A., Czernik, A. J., Huganir, R. L., Hemmings, H. C., Jr., Nairn, A. C., Greengard, P.Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.Nature 402: 669-671, 1999.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Li, Zhang, Zhu, Zhang, Lin, Xu, Yang, Hao, Zhang: "A new treatment for cognitive disorders related to in utero exposure to alcohol." in: Neural regeneration research, Vol. 8, Issue 18, pp. 1702-13, (2014) (PubMed).
抗原

CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

别名

CDK5

背景

Synonyms: Cyclin-dependent-like kinase 5,2.7.11.1,Cell division protein kinase 5,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit,CDK5,CDKN5,
Tissue Specificity: Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary. .
Background: CDK5, Cyclin-Dependent Kinase5, is also know as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

分子量

34 kDa

UniProt

Q00535

途径

Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis