CTH 抗体 (C-Term)
(5 references)Quick Overview for CTH 抗体 (C-Term) (ABIN3042672)
抗原
See all CTH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 316-331, C-Term
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原理
- Anti-Cystathionase/CTH Antibody Picoband®
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序列
- FYIKGTLQHA EIFLKN
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cystathionase/CTH Antibody (ABIN3042672). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cystathionase, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibody
CTH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E1-1B7 unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibodyCTH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal S51 unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 163-382) antibodyCTH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 14-224) antibodyCTH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) antibodyCTH 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-70) antibodyCTH 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibodyCTH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibodyCTH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 281-330) antibodyCTH 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 181-398) antibodyCTH 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Donald, L. J., Wang, H. S., Hamerton, J. L. Assignment of the gene for cystathionase (CYS) to human chromosome 16. (Abstract) Cytogenet. Cell Genet. 32: 268 only, 1982. 2. Yang, G., Wu, L., Jiang, B., Yang, W., Qi, J., Cao, K., Meng, Q., Mustafa, A. K., Mu, W., Zhang, S., Snyder, S. H., Wang, R. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 322: 587-590, 2008. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways." in: International journal of oncology, Vol. 53, Issue 1, pp. 358-370, (2018) (PubMed).
: "Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2774-80, (2016) (PubMed).
: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).
: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).
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: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
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- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
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别名
- CTH
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背景
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Synonyms: Cystathionine gamma-lyase,4.4.1.1,Cysteine-protein sulfhydrase,Gamma-cystathionase,CTH,
Background: Cystathionine gamma-lyase (or cystathionase) is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide (H2S) is physiologically generated by CTH.
Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.
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分子量
- 45 kDa
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UniProt
- P32929
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途径
- ER-Nucleus Signaling, Warburg Effect
抗原
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