我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

LIF 抗体 (C-Term)

Name: LIF 抗体 (C-Term)
SKU: ABIN3042667
Availability: OutOfStock

This anti-LIF antibody is a 兔多克隆 antibody detecting LIF in WB. Suitable for 小鼠和大鼠. This Primary Antibody has been cited in 7+ publications.

Anti-LIF antibody, Western blotting All lanes: Anti LIF at 0. (LIF 抗体 (C-Term))

1 image

(7 references)

产品编号 ABIN3042667

发货至: 中国

Quick Overview for LIF 抗体 (C-Term) (ABIN3042667)

抗原

See all LIF 抗体

LIF (Leukemia Inhibitory Factor (LIF))

适用

小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This LIF antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product LIF Primary Antibody

抗原表位
8

7

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 175-194, C-Term

原理

Anti-Leukemia inhibitory factor LIF Antibody Picoband®

序列

DKEAFQRKKL GCQLLGTYKQ

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Leukemia inhibitory factor LIF Antibody (ABIN3042667). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of mouse LIF, identical to the related rat sequence.

亚型

IgG
anti-Leukemia Inhibitory Factor (LIF) (AA 2-201) antibody
LIF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 2-201) antibody
LIF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 72-101) antibody
LIF 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 101-202) antibody
LIF 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 23-202) antibody
LIF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 72-101) antibody
LIF 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21725 unconjugated

anti-Leukemia Inhibitory Factor (LIF) (C-Term) antibody
LIF 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 23-202) antibody
LIF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (C-Term) antibody
LIF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Leukemia Inhibitory Factor (LIF) (AA 25-203) antibody
LIF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. Bamberger, A.-M., Jenatschke, S., Schulte, H. M., Loning, T., Bamberger, C. M. Leukemia inhibitory factor (LIF) stimulates the human HLA-G promoter in JEG3 choriocarcinoma cells. J. Clin. Endocr. Metab. 85: 3932-3936, 2000. 2. Sutherland, G. R., Baker, E., Hyland, V. J., Callen, D. F., Stahl, J., Gough, N. M. The gene for human leukemia inhibitory factor (LIF) maps to 22q12. Leukemia 3: 9-13, 1989.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." in: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

Dong, Sui, Huang, Wang, Hu, Xiong, Wang, Zhang: "MicroRNA-223-3p suppresses leukemia inhibitory factor expression and pinopodes formation during embryo implantation in mice." in: American journal of translational research, Vol. 8, Issue 2, pp. 1155-63, (2016) (PubMed).

Gui, Xiong, Yang, Li, Huang: "Effects of acupuncture on LIF and IL-12 in rats of implantation failure." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 67, Issue 5, pp. 383-90, (2012) (PubMed).

Xu, Sun, Li, Wu, Zhang, Feng: "Pinopodes, leukemia inhibitory factor, integrin-?3, and mucin-1 expression in the peri-implantation endometrium of women with unexplained recurrent pregnancy loss." in: Fertility and sterility, Vol. 98, Issue 2, pp. 389-95, (2012) (PubMed).

Li, Xu, Chen, Sun: "Effects of hydrosalpinx on pinopodes, leukaemia inhibitory factor, integrin beta3 and MUC1 expression in the peri-implantation endometrium." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 151, Issue 2, pp. 171-5, (2010) (PubMed).

Pei, Yu, Shi, Jia: "The effects of mifepristone on the expressions of osteopontin, interleukin-6 and leukemia inhibitory factor in the villi of early pregnant women." in: Contraception, Vol. 82, Issue 4, pp. 379-84, (2010) (PubMed).

Hu, Feng, Tang, Zhu, Lin, Yu: "LIF upregulates expression of NK-1R in NHBE cells." in: Mediators of inflammation, Vol. 2006, Issue 5, pp. 84829, (2007) (PubMed).
抗原

LIF (Leukemia Inhibitory Factor (LIF))

别名

LIF

背景

Synonyms: Leukemia inhibitory factor,LIF,Differentiation-stimulating factor,D factor,Lif,
Tissue Specificity: Not abundant, expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. .
Background: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. LIF could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.
Sequence Similarities: Belongs to the tumor necrosis factor family.

分子量

40 kDa

UniProt

P09056

途径

JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding