BAG5 抗体 (C-Term)
Quick Overview for BAG5 抗体 (C-Term) (ABIN3042660)
抗原
See all BAG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 415-429, C-Term
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原理
- Anti-Bag5 Antibody Picoband®
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序列
- QGEEKCKAAR KQAVR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Bag5 Antibody (ABIN3042660). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human BAG5, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibody
BAG5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 198-447) antibodyBAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) antibodyBAG5 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (N-Term) antibodyVerified BAG5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-448) antibodyBAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) antibodyBAG5 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (C-Term) antibodyBAG5 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Takayama S, Xie Z, Reed JC (Feb 1999). "An evolutionarily conserved family of Hsp70/Hsc70 Molecular chaperone regulators". J Biol Chem 274 (2): 781-6. 2 Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM (Dec 2004). "BAG5 inhibits parkin and enhances dopaminergic neuron degeneration". Neuron 44 (6): 931-45. 3 "Entrez Gene: BAG5 BCL2-associated athanogene 5". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- BAG5 (BCL2-Associated Athanogene 5 (BAG5))
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别名
- BAG5
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背景
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Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,
Tissue Specificity: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .
Background: BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene. The protein encoded by this gene is a member of the BAG1-related protein family. Bag5 is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death and thus promotes neurodegeneration.
Sequence Similarities: Contains 5 BAG domains.
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分子量
- 51 kDa
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途径
- SARS-CoV-2 Protein Interactome
抗原
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