Mip (AA 246-263), (C-Term) 抗体
(3 references)Quick Overview for Mip (AA 246-263), (C-Term) 抗体 (ABIN3042655)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 246-263, C-Term
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原理
- Anti-Aquaporin 0/MIP Antibody Picoband®
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序列
- NGQPEGTGEP VELKTQAL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Aquaporin 0/MIP Antibody (ABIN3042655). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0, identical to the related rat sequence, and different from the related human sequence by two amino acids.
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亚型
- IgG
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anti-Mip (AA 50-150) antibody
适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mip (AA 220-263) antibody适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mip antibody适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mip antibody适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mip (Internal Region) antibody适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mip (AA 33-206) antibody适用: Legionella pneumophila ELISA, WB 宿主: 小鼠 Monoclonal 33 unconjugated
anti-Mip (AA 232-263), (C-Term) antibody适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Human, Rat
1. Berry, V., Francis, P., Kaushal, S., Moore, A., Bhattacharya, S. Missense mutations in MIP underlie autosomal dominant 'polymorphic' and lamellar cataracts linked to 12q. Nature Genet. 25: 15-17, 2000. 2. Francis, P., Chung, J.-J., Yasui, M., Berry, V., Moore, A., Wyatt, M. K., Wistow, G., Bhattacharya, S. S., Agre, P. Functional impairment of lens aquaporin in two families with dominantly inherited cataracts. Hum. Molec. Genet. 9: 2329-2334, 2000. 3. Pisano MM, Chepelinsky AB (Mar 1992). "Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens". Genomics 11 (4): 981-90. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses." in: Antiviral research, Vol. 120, pp. 101-11, (2015) (PubMed).
: "Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-?B and NLRP3 inflammasome activation." in: Biochemical pharmacology, Vol. 94, Issue 2, pp. 142-54, (2015) (PubMed).
: "Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells." in: Blood, Vol. 120, Issue 13, pp. 2620-30, (2012) (PubMed).
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: "Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses." in: Antiviral research, Vol. 120, pp. 101-11, (2015) (PubMed).
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- Mip
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背景
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Synonyms: Lens fiber major intrinsic protein,Aquaporin-0,MIP26,MP26,Mip,
Tissue Specificity: Major component of lens fiber gap junctions.
Background: Lens fiber major intrinsic protein also called MIP26 or MP26 is a protein that in humans is encoded by the MIP gene. MIP is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. Using 2-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for MIP as probes, this gene was found that located in close proximity in region 12q13. MIP plays a crucial role in the development of a transparent eye lens. This gene may be responsible for regulating the osmolarity of the lens and interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.
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分子量
- 50 kDa
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UniProt
- P09011
抗原
-
