RGS 抗体 (C-Term)
Quick Overview for RGS 抗体 (C-Term) (ABIN3042642)
抗原
See all RGS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 624-638, C-Term
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原理
- Anti-RGS9 Antibody Picoband®
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序列
- LKSKRVANFF QIKMD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RGS9 Antibody (ABIN3042642). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RGS9, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 9 (RGS) (AA 230-350) antibody
RGS 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (AA 230-279) antibodyRGS 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, 兔, 豚鼠, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (N-Term) antibodyRGS 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (C-Term) antibodyRGS 适用: 人, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (AA 1-296) antibodyRGS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (AA 1-296) antibodyRGS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (N-Term) antibodyRGS 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 9 (RGS) (AA 149-178), (N-Term) antibodyRGS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Cabrera-Vera, T. M., Hernandez, S., Earls, L. R., Medkova, M., Sundgren-Andersson, A. K., Surmeier, D. J., Hamm, H. E. RGS9-2 modulates D2 dopamine receptor-mediated Ca(2+) channel inhibition in rat striatal cholinergic interneurons. Proc. Nat. Acad. Sci. 101: 16339-16344, 2004. 2. Hu, G., Zhang, Z., Wensel, T. G. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. J. Biol. Chem. 278: 14550-14554, 2003. 3. Sierra, D. A., Gilbert, D. J., Householder, D., Grishin, N. V., Yu, K., Ukidwe, P., Barker, S. A., He, W., Wensel, T. G., Otero, G., Brown, G., Copeland, N. G., Jenkins, N. A., Wilkie, T. M. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79: 177-185, 2002. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- RGS (Regulator of G-Protein Signaling 9 (RGS))
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别名
- RGS9
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背景
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Synonyms: Regulator of G-protein signaling 9,RGS9,RGS9,
Tissue Specificity: Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).
Background: Regulator of G-protein signaling 9, also known as RGS9 is a human gene, which codes for a protein involved in regulation of signal transduction inside cells. This gene is mapped to 17q24.1. This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Contains 1 DEP domain.
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分子量
- 56 kDa, 77 kDa
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UniProt
- O75916
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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