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LTA 抗体 (Middle Region)

LTA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042614
发货至: 中国
  • 抗原 See all LTA 抗体
    LTA (Lymphotoxin-alpha (LTA))
    抗原表位
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-88, Middle Region
    适用
    • 57
    • 21
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 54
    • 20
    • 1
    • 1
    • 1
    克隆类型
    • 52
    • 24
    • 1
    多克隆
    标记
    • 41
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This LTA antibody is un-conjugated
    应用范围
    • 47
    • 30
    • 14
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    Anti-TNF beta/LTA Antibody Picoband®
    序列
    KQNSLLWRAN TDRAFL
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-TNF beta/LTA Antibody (ABIN3042614). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human TNF beta, different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product LTA Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human
    1. Parham, Peter (2005). "Chapter 6: T-cell mediated immunity". The immune system (2nd ed.). New York: Garland Science. p. 172.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    LTA (Lymphotoxin-alpha (LTA))
    别名
    LTA (LTA 产品)
    物质类
    Chemical
    背景

    Synonyms: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB, TNFSF1,

    Tissue Specificity: Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. .

    Background: Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine. It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.

    Sequence Similarities: Belongs to the tumor necrosis factor family.

    分子量
    6 kDa
    UniProt
    P01374
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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