LTA 抗体 (Middle Region)
Quick Overview for LTA 抗体 (Middle Region) (ABIN3042614)
抗原
See all LTA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 73-88, Middle Region
-
原理
- Anti-TNF beta/LTA Antibody Picoband®
-
序列
- KQNSLLWRAN TDRAFL
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-TNF beta/LTA Antibody (ABIN3042614). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TNF beta, different from the related mouse sequence by one amino acid.
-
亚型
- IgG
-
-
anti-Lymphotoxin-alpha (LTA) (AA 49-202) antibody
LTA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 36-205) antibodyLTA 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 39-281) antibodyLTA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (Internal Region) antibodyLTA 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 1-205) antibodyLTA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 36-205) antibodyLTA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 35-191) antibodyLTA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 46-72) antibodyLTA 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21239 unconjugated
anti-Lymphotoxin-alpha (LTA) (Middle Region) antibodyLTA 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin-alpha (LTA) (AA 116-203) antibodyLTA 适用: 斑马鱼 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Parham, Peter (2005). "Chapter 6: T-cell mediated immunity". The immune system (2nd ed.). New York: Garland Science. p. 172. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- LTA (Lymphotoxin-alpha (LTA))
-
别名
- LTA
-
物质类
- Chemical
-
背景
-
Synonyms: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB, TNFSF1,
Tissue Specificity: Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. .
Background: Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine. It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.
Sequence Similarities: Belongs to the tumor necrosis factor family.
-
分子量
- 6 kDa
-
UniProt
- P01374
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-
