P-Cadherin 抗体 (Middle Region)
Quick Overview for P-Cadherin 抗体 (Middle Region) (ABIN3042613)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 612-626, Middle Region
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原理
- Anti-P-Cadherin-3 CDH3-Antibody Picoband®
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序列
- QDTYDVHLSL SDHGN
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-P-Cadherin-3 CDH3-Antibody (ABIN3042613). Tested in IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human P cadherin, different from the mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-P-Cadherin (CDH3) (AA 371-660) antibody
CDH3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (N-Term) antibodyCDH3 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 625-725) antibodyCDH3 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 24-350) antibodyCDH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (C-Term) antibodyCDH3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 117-360) antibodyCDH3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 187-236) antibodyCDH3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 114-142), (N-Term) antibodyCDH3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry , 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (Dec 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics 14 (2): 488-90. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- P-Cadherin (CDH3)
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别名
- CDH3
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背景
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Synonyms: Cadherin-3,Placental cadherin,P-cadherin,CDH3,CDHP,
Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines. .
Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Sequence Similarities: Contains 5 cadherin domains.
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分子量
- 120 kDa
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UniProt
- P22223
抗原
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