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CCL4 抗体 (C-Term)

This anti-CCL4 antibody is a 兔 多克隆 antibody detecting CCL4 in WB. Suitable for 小鼠.
产品编号 ABIN3042607
发货至: 中国

Quick Overview for CCL4 抗体 (C-Term) (ABIN3042607)

抗原

See all CCL4 抗体
CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This CCL4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 74-88, C-Term

    原理

    Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody Picoband®

    序列

    CANPSEPWVT EYMSD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody (ABIN3042607). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse CCL4.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    1. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K (June 1990). Nucleic Acids Res. 18 (11): 3261-70. 2. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (December 2001). "B cells and professional APCs recruit regulatory T cells via CCL4". Nat. Immunol. 2 (12): 1126-32. 3. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995). Science (journal) 270 (5243): 1811-5. 4. Kamin-Lewis R, Abdelwahab SF, Trang C, Baker A, DeVico AL, Gallo RC, Lewis GK (July 2001).

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

    别名

    CCL4

    背景

    Synonyms: C-C motif chemokine 4,Immune activation protein 2,ACT-2,ACT2,Macrophage inflammatory protein 1-beta,MIP-1-beta,Protein H400,SIS-gamma,Small-inducible cytokine A4,Ccl4,Mip1b, Scya4,

    Tissue Specificity: Ubiquitous. Isoform Mdm2-A, isoform Mdm2-B, isoform Mdm2-C, isoform Mdm2-D, isoform Mdm2-E, isoform Mdm2-F and isoform Mdm2-G are observed in a range of cancers but absent in normal tissues.

    Background: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al. (1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al. (1990): 17q21-q23 rather than 17q11-q21.

    Sequence Similarities: Belongs to the MDM2/MDM4 family.

    分子量

    90 kDa

    UniProt

    P14097
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