AVPR1A 抗体 (Middle Region)
Quick Overview for AVPR1A 抗体 (Middle Region) (ABIN3042582)
抗原
See all AVPR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-173, Middle Region
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原理
- Anti-Vasopressin V1a receptor AVPR1A Antibody Picoband®
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序列
- HPLKTLQQPA RRSRLMIAT
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Vasopressin V1a receptor AVPR1A Antibody (ABIN3042582). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A, different from the related human and mouse sequences by one amino acid.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Birnbaumer, M. Vasopressin receptors. Trends Endocr. Metab. 11: 406-410, 2000. 2. Caldwell HK, Lee HJ, Macbeth AH, Young WS (2008). "Vasopressin: behavioral roles of an 'original' neuropeptide". Prog Neurobiol 84 (1): 1-24. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))
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别名
- AVPR1A
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背景
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Synonyms: Vasopressin V1a receptor;V1aR;AVPR V1a;Antidiuretic hormone receptor 1a;Vascular/hepatic-type arginine vasopressin receptor;Avpr1a;
Tissue Specificity: Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex. .
Background: Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
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分子量
- 47 kDa
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UniProt
- P30560
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Response to Water Deprivation, Regulation of Carbohydrate Metabolic Process
抗原
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