Reticulon 3 抗体 (C-Term)
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北京 101111
Quick Overview for Reticulon 3 抗体 (C-Term) (ABIN3042575)
抗原
See all Reticulon 3 (RTN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1017-1032, C-Term
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原理
- Rabbit IgG polyclonal antibody for Reticulon-3(RTN3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
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序列
- EKIQAKLPGI AKKKAE
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
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Rabbit IgG polyclonal antibody for Reticulon-3(RTN3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: reticulon 3
Protein Name: Reticulon-3 -
纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RTN3(1017-1032aa EKIQAKLPGIAKKKAE), identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Reticulon 3 (RTN3) antibody
RTN3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 10A8 unconjugated
anti-Reticulon 3 (RTN3) (AA 750-800) antibodyRTN3 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 3 (RTN3) antibodyRTN3 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Reticulon 3 (RTN3) (AA 1-236) antibodyRTN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Reticulon 3 (RTN3) (AA 1-236) antibodyRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 3 (RTN3) (C-Term) antibodyRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Reticulon 3 (RTN3)
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别名
- RTN3
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背景
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Reticulon-3, also known as RTN3 or NSPL2, is a protein that in humans is encoded by the RTN3 gene. It is mapped to 11q13, which is between markers D11S4535 and D11S4627. This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1(BACE1), and the production of amyloid-beta. RTN3 colocalized with BACE1 in neurons of human brain gray matter, and overexpression of RTN3 in vitro inhibited BACE1 activity and decreased amyloid precursor protein processing.
Synonyms: ASYIP antibody|Neuroendocrine specific protein like 2 antibody|Neuroendocrine-specific protein-like 2 antibody|Neuroendocrine-specific protein-like II antibody|NSP like protein II antibody|NSP-like protein 2 antibody|NSP-like protein II antibody|NSPL2 antibody|NSPLII antibody|Reticulon 3 antibody|Reticulon-3 antibody|Reticulon3 antibody|Rtn3 antibody|RTN3_HUMAN antibody -
UniProt
- O95197
抗原
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