CARM1 抗体 (Middle Region)
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北京 101111
Quick Overview for CARM1 抗体 (Middle Region) (ABIN3042568)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-PRMT4/CARM1 Antibody
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序列
- HLAPFTDEQL YMEQFTKA
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-PRMT4/CARM1 Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PRMT4, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) antibody
CARM1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3H2 unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 409-608) antibodyCARM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 346-377) antibodyCARM1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB09614 unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 209-379) antibodyCARM1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 346-377) antibodyCARM1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) antibodyCARM1 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (pSer228) antibodyCARM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) antibodyCARM1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB75 unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 411-510) antibodyCARM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coactivator-Associated Arginine Methyltransferase 1 (CARM1) (AA 284-381) antibodyCARM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G9 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- CARM1
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背景
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Background: CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. This gene is mapped to 19p13.2. CARM1 is a regulator of cyclin E1 and DHFR mRNA expression. Its main function includes catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. CARM1 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.
Gene Full Name: coactivator associated arginine methyltransferase 1
Sequence Similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family.
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分子量
- 66 kDa
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基因ID
- 10498
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UniProt
- Q86X55
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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