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EPB41L1 抗体 (C-Term)

EPB41L1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042566
发货至: 中国
  • 抗原 See all EPB41L1 抗体
    EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 585-604, C-Term
    适用
    • 10
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    • 4
    克隆类型
    • 9
    • 1
    多克隆
    标记
    • 10
    This EPB41L1 antibody is un-conjugated
    应用范围
    • 10
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    Anti-Band 4.1-like protein 1 EPB41L1 Antibody Picoband®
    序列
    QDQERDTVFL KDNHLAIERK
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Band 4.1-like protein 1 EPB41L1 Antibody (ABIN3042566). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human EPB41L1, different from the related mouse and rat sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product EPB41L1 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    1. Binda, Alicia V, Kabbani Nadine, Lin Ridwan, Levenson Robert (September 2002). "D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N". Mol. Pharmacol. (United States) 62 (3): 507-13. 2. Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D.-T., Yoshizawa, Y., Higashi, K., Park, A.-R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., and 22 others. Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am. J. Hum. Genet. 88: 306-316, 2011. Note: Erratum: Am. J. Hum. Genet. 88: 516 only, 2011. 3. Kim AC, Van Huffel C, Lutchman M, Chishti AH (June 1998). "Radiation hybrid mapping of EPB41L1, a novel protein 4.1 homologue, to human chromosome 20q11.2-q12". Genomics 49 (1): 165-6.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))
    别名
    EPB41L1 (EPB41L1 产品)
    背景

    Synonyms: Band 4.1-like protein 1,Neuronal protein 4.1,4.1N,EPB41L1,KIAA0338,

    Tissue Specificity: Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

    Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. EPB41L1 has been shown to interact with ITPR1, Dopamine receptor D2, Dopamine receptor D3, CENTG1 and Nuclear mitotic apparatus protein 1.

    Sequence Similarities: Contains 1 FERM domain.

    分子量
    99 kDa
    UniProt
    Q9H4G0
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