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Huntingtin 抗体 (C-Term)

Name: Huntingtin 抗体 (C-Term)
SKU: ABIN3042565
Availability: OutOfStock

HTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Anti-Huntingtin antibody, All Western blottingAll lanes: Anti-HTT at 0. (Huntingtin 抗体 (C-Term))

1 image

产品编号 ABIN3042565

发货至: 中国

Datasheet as PDF

抗原 See all Huntingtin (HTT) 抗体

Huntingtin (HTT)
抗原表位
15

6

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 3106-3121, C-Term
适用
63

46

37

6

3

2

2

1

1

1

1

1

1

1

1

1

1
人
宿主
60

21

2
兔
Compatible Secondaries
克隆类型
53

29
多克隆
标记
55

3

3

3

3

3

3

3

1

1

1

1

1

1

1
This Huntingtin antibody is un-conjugated
应用范围
40

33

25

14

14

13

13

9

7

4

4

2

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Huntingtin(HTT) detection. Tested with WB in Human,Mouse,Rat.

序列

ELDRRAFQSV LEVVAA

交叉反应（详细）

Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

产品特性

Rabbit IgG polyclonal antibody for Huntingtin(HTT) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: huntingtin
Protein Name: Huntingtin

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Huntingtin(3106-3121aa ELDRRAFQSVLEVVAA), different from the related mouse and rat sequences by two amino acids.

亚型

IgG

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HTT 适用: 人, 兔 WB, IHC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
抗原

Huntingtin (HTT)

别名

HTT (HTT 产品)

别名

HTT antibody, hd antibody, ZHD antibody, CG9995 antibody, Dmel\\CG9995 antibody, HD antibody, Hsap\\HD antibody, Htt antibody, dHtt antibody, dhtt antibody, SLC6A4 antibody, huntington antibody, it15 antibody, htt antibody, IT15 antibody, AI256365 antibody, C430023I11Rik antibody, Hd antibody, Hdh antibody, huntingtin antibody, HTT antibody, htt antibody, LOC373520 antibody, Htt antibody

背景

The huntingtin gene, also called HTT or HD(Huntington disease) gene, is the IT15("interesting transcript 15") gene which codes for a protein called the huntingtin protein. It is mapped to 4p16.3. The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents. HTT upregulates the expression of Brain Derived Neurotrophic Factor(BDNF) at the transcription level, and this gene is required for normal development. The HTT protein is involved in vesicle trafficking as it interacts with HIP1, a clathrin-binding protein, to mediate endocytosis, the absorption of materials into a cell. HTT was also visualized as punctate staining likely to represent nerve endings. What's more, wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.

Synonyms: AI256365 antibody|C430023I11Rik antibody|HD antibody|HD protein antibody|HDH antibody|HTT antibody|Huntingtin antibody|HUNTINGTON CHOREA antibody|Huntington disease protein antibody|IT 15 antibody|IT15 antibody|OTTMUSP00000026909 antibody|ZHD antibody

UniProt

P42858

途径

PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport