SOX7 抗体 (C-Term)
Quick Overview for SOX7 抗体 (C-Term) (ABIN3042550)
抗原
See all SOX7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-388, C-Term
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原理
- Anti-SOX7 Antibody Picoband®
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序列
- LISVLADATA TYYNSYSVS
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-SOX7 Antibody (ABIN3042550). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (Middle Region) antibody
SOX7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (AA 42-100) antibodySOX7 适用: 人, 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) antibodySOX7 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (AA 224-258) antibodySOX7 适用: 人 WB 宿主: 兔 Polyclonal RB51583 unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (N-Term) antibodySOX7 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (AA 250-350) antibodySOX7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (N-Term) antibodySOX7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (Middle Region) antibodySOX7 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (C-Term) antibodySOX7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 7 (SOX7) (AA 310-339) antibodySOX7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Murakami, A., Shen, H., Ishida, S., Dickson, C. SOX7 and GATA-4 are competitive activators of Fgf-3 transcription. J. Biol. Chem. 279: 28564-28573, 2004. 2. "Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells." Guo L., Zhong D., Lau S., Liu X., Dong X.Y., Sun X., Yang V.W., Vertino P.M., Moreno C.S., Varma V., Dong J.T., Zhou W. Mol. Cancer Res. 6:1421-1430(2008). 3. Takash, W., Canizares, J., Bonneaud, N., Poulat, F., Mattei, M.-G., Jay, P., Berta, P. SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signaling. Nucleic Acids Res. 29: 4274-4283, 2001. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))
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别名
- SOX7
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背景
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Synonyms: Transcription factor SOX-7,SOX7,
Tissue Specificity: Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. .
Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 42 kDa
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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