ST5 抗体 (Middle Region)
Quick Overview for ST5 抗体 (Middle Region) (ABIN3042548)
抗原
See all ST5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 571-586, Middle Region
-
原理
- Anti-ST5 Antibody Picoband®
-
序列
- KRHSHDDMLL LAQLSL
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-ST5 Antibody (ABIN3042548). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ST5, different from the related mouse and rat sequences by one amino acid.
-
亚型
- IgG
-
-
anti-Suppression of Tumorigenicity 5 (ST5) (AA 3-280) antibody
ST5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (Internal Region) antibodyST5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (Internal Region) antibodyST5 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (AA 68-88) antibodyST5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (AA 387-436) antibodyST5 适用: 人, Cow, 豚鼠, 马, 兔, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (AA 1106-1137), (C-Term) antibodyST5 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB2071 unconjugated
anti-Suppression of Tumorigenicity 5 (ST5) (Internal Region) antibodyST5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ST5 suppression of tumorigenicity 5" 2. Lichy JH, Modi WS, Seuanez HN, Howley PM (Nov 1992). "Identification of a human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells".Cell Growth Differ 3 (8): 541-8. 3. Trautmann, U., Vikkula, M., Winterpacht, A., FitzPatrick, D. R., Rauch, A. Disruption of ST5 is associated with mental retardation and multiple congenital abnormalities. J. Med. Genet. 47: 91-98, 2010. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- ST5 (Suppression of Tumorigenicity 5 (ST5))
-
别名
- ST5
-
背景
-
Synonyms: Suppression of tumorigenicity 5 protein,DENN domain-containing protein 2B,HeLa tumor suppression 1,ST5,DENND2B, HTS1,
Tissue Specificity: Widely expressed with the exception of peripheral blood lymphocytes. Isoform 1 is expressed in several epithelial and fibroblast (including tumorigenic) but absent in lymphoid cell lines (at protein level). Isoform 3 is expressed in primary cell or weakly tumorigenic but not in tumorigenic cell lines (at protein level). .
Background: Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Sequence Similarities: Contains 1 dDENN domain.
-
分子量
- 126 kDa
-
UniProt
- P78524
抗原
-
