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ST5 抗体 (Middle Region)

This anti-ST5 antibody is a 兔 多克隆 antibody detecting ST5 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3042548
发货至: 中国
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Quick Overview for ST5 抗体 (Middle Region) (ABIN3042548)

抗原

See all ST5 抗体
ST5 (Suppression of Tumorigenicity 5 (ST5))

适用

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人, 小鼠, 大鼠

宿主

  • 34
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克隆类型

  • 34
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多克隆

标记

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This ST5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 571-586, Middle Region

    原理

    Anti-ST5 Antibody

    序列

    KRHSHDDMLL LAQLSL

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ST5 Antibody (ABIN3042548). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human ST5, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ST5 (Suppression of Tumorigenicity 5 (ST5))

    别名

    ST5

    背景

    Synonyms: Suppression of tumorigenicity 5 protein,DENN domain-containing protein 2B,HeLa tumor suppression 1,ST5,DENND2B, HTS1,

    Tissue Specificity: Widely expressed with the exception of peripheral blood lymphocytes. Isoform 1 is expressed in several epithelial and fibroblast (including tumorigenic) but absent in lymphoid cell lines (at protein level). Isoform 3 is expressed in primary cell or weakly tumorigenic but not in tumorigenic cell lines (at protein level). .

    Background: Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

    Sequence Similarities: Contains 1 dDENN domain.

    分子量

    126 kDa

    UniProt

    P78524
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