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GM-CSF 抗体 (AA 18-141)

Name: GM-CSF 抗体 (AA 18-141)
SKU: ABIN3042527
Availability: OutOfStock

CSF2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti-GM-CSF Picoband antibody, All lanes: Anti-GM-CSF at 0. (GM-CSF 抗体 (AA 18-141))

Anti-GM-CSF Picoband antibody, IHC(P): Mouse Spleen Tissue (GM-CSF 抗体 (AA 18-141))

IHC

3 images

(1 reference)

产品编号 ABIN3042527

发货至: 中国

Datasheet as PDF

抗原 See all GM-CSF (CSF2) 抗体

GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
抗原表位
20

12

10

8

3

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1
AA 18-141
适用
122

46

24

10

10

4

4

3

3

2

2

2

2
小鼠
宿主
106

35

31

4

1
兔
Compatible Secondaries
克隆类型
111

66
多克隆
标记
101

23

9

6

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GM-CSF antibody is un-conjugated
应用范围
133

76

41

32

29

27

26

20

15

14

10

5

4

3

3

2

2

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-GM-CSF/CSF2 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-GM-CSF/CSF2 Antibody Picoband® (ABIN3042527). Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived mouse GM-CSF recombinant protein (Position: A18-K141). Mouse GM-CSF shares 54% and 70% amino acid (aa) sequences identity with human and rat GM-CSF, respectively.

亚型

IgG

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anti-Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-144) antibody
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anti-Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 1-144) antibody
CSF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse
1. Le Beau, M. M., Espinosa, R., III, Neuman, W. L., Stock, W., Roulston, D., Larson, R. A., Keinanen, M., Westbrook, C. A.Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.Proc. Nat. Acad. Sci. 90: 5484-5488, 1993. 2. Park, B. K., Zhang, H., Zeng, Q., Dai, J., Keller, E. T., Giordano, T., Gu, K., Shah, V., Pei, L., Zarbo, R. J., McCauley, L., Shi, S., Chen, S., Wang, C.-Y.NF-kappa-B in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.Nature Med. 13: 62-69, 2007. 3. Uchida, K., Beck, D. C., Yamamoto, T., Berclaz, P.-Y., Abe, S., Staudt, M. K., Carey, B. C., Filippi, M.-D., Wert, S. E., Denson, L. A., Puchalski, J. T., Hauck, D. M., Trapnell, B. C.GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.New Eng. J. Med. 356: 567-579, 2007.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Fang, Shi, Meng, Li, Peng: "The Balance between Conventional DCs and Plasmacytoid DCs Is Pivotal for Immunological Tolerance during Pregnancy in the Mouse." in: Scientific reports, Vol. 6, pp. 26984, (2018) (PubMed).
抗原

GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

别名

CSF2 (CSF2 产品)

背景

Synonyms: Granulocyte-macrophage colony-stimulating factor,GM-CSF,Colony-stimulating factor,CSF,Csf2,Csfgm,
Tissue Specificity: Synthesized exclusively by adipocytes and secreted into plasma.
Background: GM-CSF, Granulocyte-macrophage colony-stimulating factor, is a protein secreted by macrophages, T cells, mast cells, endothelial cells, and fibroblasts. By fluorescence in situ hybridization, the GM-CSF gene is mapped to 5q31.1. GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. GM-CSF is an essential regulator of neutrophil function.
Sequence Similarities: Belongs to the GM-CSF family.

分子量

17 kDa

UniProt

P01587

途径

JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin