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- 抗原 See all CNTF 抗体
- CNTF (Ciliary Neurotrophic Factor (CNTF))
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抗原表位
- AA 2-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CNTF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-CNTF Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-CNTF Antibody Picoband® (ABIN3042520). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CNTF recombinant protein (Position: A2-M200). Human CNTF shares 83% and 84% amino acid (aa) sequences identity with mouse and rat CNTF, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CNTF Primary Antibody
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anti-Ciliary Neurotrophic Factor (CNTF) (C-Term) antibody
CNTF 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 21-150) antibodyCNTF 适用: 人, 大鼠, 兔 WB, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 4-196) antibodyCNTF 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 181-216), (C-Term) antibodyCNTF 适用: 人 WB 宿主: 兔 Polyclonal RB52493 unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Lam, A., Fuller, F., Miller, J., Kloss, J., Manthorpe, M., Varon, S., Cordell, B. Sequence and structural organization of the human gene encoding ciliary neurotrophic factor. Gene 102: 271-276, 1991. 2. Watt, M. J., Dzamko, N., Thomas, W. G., Rose-John, S., Ernst, M., Carling, D., Kemp, B. E., Febbraio, M. A., Steinberg, G. R. CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nature Med. 12: 541-548, 2006. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- CNTF (Ciliary Neurotrophic Factor (CNTF))
- 别名
- CNTF (CNTF 产品)
- 背景
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Synonyms: Ciliary neurotrophic factor,CNTF,CNTF,
Tissue Specificity: Nervous system.
Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The CNTF gene is located on chromosome 11, as determined using human-hamster somatic cell hybrids. The CNTF protein is highly conserved in evolution. The amino acid (aa) sequences of rat and rabbit CNTF translated from cDNAs display approx. 85 % homology with the deduced aa sequence encoding human CNTF. CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.
Sequence Similarities: Belongs to the CNTF family.
- 分子量
- 28 kDa
- 基因ID
- 1270
- UniProt
- P26441
- 途径
- JAK/STAT Signaling
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