CCL18 抗体 (AA 21-89)
Quick Overview for CCL18 抗体 (AA 21-89) (ABIN3042511)
抗原
See all CCL18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-89
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原理
- Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband® (ABIN3042511). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCL18 recombinant protein (Position: A21-A89).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) (AA 1-89) antibody
CCL18 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) (AA 21-89) antibodyCCL18 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) (C-Term) antibodyCCL18 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) (Middle Region) antibodyCCL18 适用: 人, 犬, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) antibodyCCL18 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) (AA 21-89) antibodyCCL18 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, -
ELISA(Cap) , 1-5 μg/mL, Human
1. Hieshima k, I. T. (August 1997). "A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes". Journal of Immunology 159 (3): 1140-1149. 2. Tasaki, Y., Fukuda, S., Iio, M., Miura, R., Imai, T., Sugano, S., Yoshie, O., Hughes, A. et al. (1999). "Chemokine PARC Gene (SCYA18) Generated by Fusion of Two MIP-1α/LD78α-like Genes, ,". Genomics 55 (3): 353-357. 3. Hieshima, K., Imai, T., Baba, M., Shoudai, K., Ishizuka, K., Nakagawa, T., Tsuruta, J., Takeya, M., Sakaki, Y., Takatsuki, K., Miura, R., Opdenakker, G., Van Damme, J., Yoshie, O., Nomiyama, H. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1-alpha/LD78-alpha and chemotactic for T lymphocytes, but not for monocytes. J. Immun. 159: 1140-1149, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
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别名
- CCL18
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背景
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Synonyms: C-C motif chemokine 18,Alternative macrophage activation-associated CC chemokine 1,AMAC-1,CC chemokine PARC,Dendritic cell chemokine 1,DC-CK1,Macrophage inflammatory protein 4,MIP-4,Pulmonary and activation-regulated chemokine,Small-inducible cytokine A18,CCL18 (1-68),CCL18 (3-69),CCL18 (4-69),CCL18,AMAC1, DCCK1, MIP4, PARC, SCYA18,
Tissue Specificity: Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. .
Background: Macrophage Inflammatory Protein 4, also known as CCL18, is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine). CCL18 is approximately 60 % identical in amino acid sequence to CCL3. By analysis of a previously mapped CCL18 from 17q11.2, it is determined that the PARC gene is located within 1 of the 2 clusters of CC chemokine genes in this region. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes. Beside, CCL18 recruits Th2 cells and basophils and may play a predominant role in allergic asthma.
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
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分子量
- 19 kDa
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基因ID
- 6362
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UniProt
- P55774
抗原
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