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LOXL1 抗体 (C-Term)

LOXL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042507
发货至: 中国
  • 抗原 See all LOXL1 抗体
    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
    抗原表位
    • 9
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 397-425, C-Term
    适用
    • 43
    • 17
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 44
    • 6
    克隆类型
    • 46
    • 4
    多克隆
    标记
    • 23
    • 10
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LOXL1 antibody is un-conjugated
    应用范围
    • 30
    • 18
    • 11
    • 8
    • 8
    • 8
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-LOXL1 Antibody Picoband®
    序列
    AEEKCLASTA YAPEATDYDV RVLLRFPQR
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-LOXL1 Antibody Picoband® (ABIN3042507). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1, different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product LOXL1 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25". The Journal of Biological Chemistry 268 (25): 18435-7. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. (United States) 36 (2): 178-82. 3. "Entrez Gene: LOXL1 lysyl oxidase-like 1".
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
    别名
    LOXL1 (LOXL1 产品)
    背景

    Synonyms: Lysyl oxidase homolog 1,1.4.3.-,Lysyl oxidase-like protein 1,LOL,LOXL1,LOXL,

    Tissue Specificity: Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina. .

    Background: Lysyl oxidase homolog 1, also known as?LOXL1, is an?enzyme?which in humans is encoded by the?LOXL1?gene. This gene encodes a member of the?lysyl oxidase?gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in?collagens?and?elastin. A highly conserved amino acid sequence at the C-terminus?end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The?N-terminus?is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and?chemotaxis?to each member of the family.

    分子量
    63 kDa
    基因ID
    4016
    UniProt
    Q08397
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