LOXL1 抗体 (C-Term)
Quick Overview for LOXL1 抗体 (C-Term) (ABIN3042507)
抗原
See all LOXL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 397-425, C-Term
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原理
- Anti-LOXL1 Antibody Picoband®
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序列
- AEEKCLASTA YAPEATDYDV RVLLRFPQR
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-LOXL1 Antibody Picoband® (ABIN3042507). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25". The Journal of Biological Chemistry 268 (25): 18435-7. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. (United States) 36 (2): 178-82. 3. "Entrez Gene: LOXL1 lysyl oxidase-like 1". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
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别名
- LOXL1
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背景
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Synonyms: Lysyl oxidase homolog 1,1.4.3.-,Lysyl oxidase-like protein 1,LOL,LOXL1,LOXL,
Tissue Specificity: Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina. .
Background: Lysyl oxidase homolog 1, also known as?LOXL1, is an?enzyme?which in humans is encoded by the?LOXL1?gene. This gene encodes a member of the?lysyl oxidase?gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in?collagens?and?elastin. A highly conserved amino acid sequence at the C-terminus?end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The?N-terminus?is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and?chemotaxis?to each member of the family.
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分子量
- 63 kDa
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基因ID
- 4016
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UniProt
- Q08397
抗原
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