LOX 抗体 (Middle Region)
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北京 101111
Quick Overview for LOX 抗体 (Middle Region) (ABIN3042506)
抗原
See all LOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-268, Middle Region
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原理
- Anti-LOX Antibody
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序列
- AEENCLASTA YRADVRDYDH RVLLRFPQR
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-LOX Antibody (ABIN3042506). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human LOX, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LOX (Lysyl Oxidase (LOX))
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别名
- LOX
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背景
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Synonyms: Protein-lysine 6-oxidase;1.4.3.13;Lysyl oxidase;LOX;
Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas. .
Background: Lysyl oxidase (LOX), also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 31 kDa
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基因ID
- 4015
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UniProt
- P28300
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途径
- SARS-CoV-2 Protein Interactome
抗原
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