LOX 抗体 (Middle Region)
Quick Overview for LOX 抗体 (Middle Region) (ABIN3042506)
抗原
See all LOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-268, Middle Region
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原理
- Anti-LOX Antibody Picoband®
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序列
- AEENCLASTA YRADVRDYDH RVLLRFPQR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-LOX Antibody Picoband® (ABIN3042506). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human LOX, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Lysyl Oxidase (LOX) (AA 213-417) antibody
LOX 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 22-168) antibodyLOX 适用: 人, 大鼠, 犬 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C4 unconjugated
anti-Lysyl Oxidase (LOX) antibodyLOX 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Lysyl Oxidase (LOX) antibodyLOX 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 207-411) antibodyLOX 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 174-417) antibodyLOX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 23-285) antibodyLOX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 234-260) antibodyLOX 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 163-411) antibodyLOX 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) antibody (Biotin)LOX 适用: 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hamalainen, E.-R., Jones, T. A., Sheer, D., Taskinen, K., Pihlajaniemi, T., Kivirikko, K. I. Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2. Genomics 11: 508-516, 1991. 2. Kuivaniemi, H., Savolainen, E.-R., Kivirikko, K. I. Human placental lysyl oxidase: purification, partial characterization, and preparation of two specific antisera to the enzyme. J. Biol. Chem. 259: 6996-7002, 1984. 3. Li, W., Nellaiappan, K., Strassmaier, T., Graham, L., Thomas, K. M., Kagan, H. M. Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proc. Nat. Acad. Sci. 94: 12817-12822, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LOX (Lysyl Oxidase (LOX))
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别名
- LOX
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背景
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Synonyms: Protein-lysine 6-oxidase;1.4.3.13;Lysyl oxidase;LOX;
Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas. .
Background: Lysyl oxidase (LOX), also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 31 kDa
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基因ID
- 4015
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UniProt
- P28300
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途径
- SARS-CoV-2 Protein Interactome
抗原
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