Otoferlin 抗体 (C-Term)
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Quick Overview for Otoferlin 抗体 (C-Term) (ABIN3042499)
抗原
See all Otoferlin (OTOF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Otoferlin Antibody
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序列
- QIWDADHFSA DDFLGAIELD LNRFPRGAKT AKQ
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-Otoferlin Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Otoferlin, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Otoferlin (OTOF) (AA 181-196) antibody
KO Validated OTOF 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Otoferlin (OTOF) antibodyOTOF 适用: 斑马鱼 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Otoferlin (OTOF)
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别名
- OTOF
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背景
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Background: Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.
Gene Full Name: otoferlin
Sequence Similarities: Belongs to the ferlin family.
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分子量
- 227 kDa
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基因ID
- 9381
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UniProt
- Q9HC10
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途径
- Sensory Perception of Sound, Synaptic Vesicle Exocytosis
抗原
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