Otoferlin 抗体 (C-Term)
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- 抗原 See all Otoferlin (OTOF) 抗体
- Otoferlin (OTOF)
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抗原表位
- AA 1831-1863, C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Otoferlin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Otoferlin(OTOF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- QIWDADHFSA DDFLGAIELD LNRFPRGAKT AKQ
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Otoferlin(OTOF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: otoferlin
Protein Name: Otoferlin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Otoferlin (1831-1863aa QIWDADHFSADDFLGAIELDLNRFPRGAKTAKQ), identical to the related mouse and rat sequences.
- 亚型
- IgG
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anti-Otoferlin (OTOF) antibody
OTOF 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Otoferlin (OTOF) (AA 196-211), (Isoform 1) antibodyOTOF 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Otoferlin (OTOF)
- 别名
- OTOF (OTOF 产品)
- 别名
- OTOF antibody, Otof antibody, AUNB1 antibody, DFNB6 antibody, DFNB9 antibody, FER1L2 antibody, NSRD9 antibody, fj34b10 antibody, si:dkey-181f18.3 antibody, wu:fj34b10 antibody, otoferlin antibody, putative otoferlin antibody, otoferlin a antibody, OTOF antibody, LOC5565414 antibody, CpipJ_CPIJ002471 antibody, CpipJ_CPIJ010863 antibody, Smp_163750 antibody, otof antibody, Otof antibody, otofa antibody
- 背景
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Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.
Synonyms: AUNB1 antibody|Deafness, autosomal recessive 9 antibody|DFNB6 antibody|DFNB9 antibody|Fer 1 like protein 2 antibody|Fer-1-like protein 2 antibody|FER1L2 antibody|NSRD9 antibody|Otof antibody|OTOF_HUMAN antibody|Otoferlin antibody - 基因ID
- 9381
- 途径
- Sensory Perception of Sound, Synaptic Vesicle Exocytosis
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