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PTOV1 抗体 (C-Term)

This anti-PTOV1 antibody is a 兔 多克隆 antibody detecting PTOV1 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN3042495
发货至: 中国

Quick Overview for PTOV1 抗体 (C-Term) (ABIN3042495)

抗原

See all PTOV1 抗体
PTOV1 (Prostate Tumor Overexpressed 1 (PTOV1))

适用

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人, 大鼠

宿主

  • 40

克隆类型

  • 40
多克隆

标记

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This PTOV1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 385-414, C-Term

    原理

    Anti-PTOV1 Antibody Picoband®

    序列

    NFVNGIRRVI ANQQQVLQRN LEQEQQQRGM

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-PTOV1 Antibody (ABIN3042495). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Rat, Human
    1. "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1". 2. Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol 25 (5): 1900-11. 3. Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003)."PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol 162 (3): 897-905.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PTOV1 (Prostate Tumor Overexpressed 1 (PTOV1))

    别名

    PTOV1

    背景

    Synonyms: Prostate tumor-overexpressed gene 1 protein,PTOV-1,Activator interaction domain-containing protein 2,PTOV1,ACID2,PP642, UNQ6127/PRO20092,

    Tissue Specificity: Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. .

    Background: Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.

    Sequence Similarities: Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.

    分子量

    47 kDa

    基因ID

    53635
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